Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q05043

Entry ID Method Resolution Chain Position Source
AF-Q05043-F1 Predicted AlphaFoldDB

20 variants for Q05043

Variant ID(s) Position Change Description Diseaes Association Provenance
s13-330810 7 E>* No SGRP
s13-330955 55 P>R No SGRP
s13-330961 57 I>T No SGRP
s13-331021 77 S>F No SGRP
s13-331045 85 S>L No SGRP
s13-331170 127 N>Y No SGRP
s13-331269 160 H>Y No SGRP
s13-331300 170 P>H No SGRP
s13-331333 181 D>G No SGRP
s13-331450 220 L>Q No SGRP
s13-331449 220 L>V No SGRP
s13-331473 228 F>I No SGRP
s13-331507 239 C>Y No SGRP
s13-331675 295 S>L No SGRP
s13-331688 299 M>I No SGRP
s13-331754 321 M>I No SGRP
s13-331783 331 I>S No SGRP
s13-331786 332 S>L No SGRP
s13-331909 373 Q>P No SGRP
s13-331918 376 N>S No SGRP

No associated diseases with Q05043

No regional properties for Q05043

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q05043

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
aerobic respiration The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
mitochondrial transcription The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.
transcription by RNA polymerase II The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKDLNPEMGK FATTKGPPQD NRGMVDIATL PNFPANRSGT PREEMYLAPN KMETPRILNM
70 80 90 100 110 120
NMVPDYLQKE NFSPDFSSAT VSAKSSPVNV THDESLPLGT IESNSTKDSK YAVQRQQQQV
130 140 150 160 170 180
VDFIENNMQL LSSETLNFRS DIMKTLELPI PKRRDIKGNH LSKLLFAKSP LTINTYCQFY
190 200 210 220 230 240
DRRTKRICNQ EMIWKDKNSR EKHGSRKYQR HLSKVHDVQL TPNNFTEFFD HNSPLFQECY
250 260 270 280 290 300
DYQSRLMRDL LVEPDAKFKE KKKKKKGDVN GNHPETGSSL INHQVQQQNV RELQSKIAMN
310 320 330 340 350 360
DLIEILIDLN IPFSVLDYQP MRNWLIKYSI ISTDTLPDEV YFKTDPGVNE LEHNSSNLNN
370
SNSGTPHNHN QNQHTN