Q04U31

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)
KEGG Pathway
lbj:LBJ_0946
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-291 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q04U31

Entry ID Method Resolution Chain Position Source
AF-Q04U31-F1 Predicted AlphaFoldDB

No variants for Q04U31

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q04U31

No associated diseases with Q04U31

5 regional properties for Q04U31

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 347 - 516 IPR000795
domain Small GTP-binding protein domain 350 - 506 IPR005225
domain Translation initiation factor IF-2, N-terminal 274 - 323 IPR006847
domain Translation initiation factor IF- 2, domain 3 630 - 741 IPR023115
domain Translation initiation factor IF-2, domain II 522 - 617 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEDKNKTIKE TLQGAADAGK RKKLIIKKKG DENSAPSSAS PKKETIAESA PVKPLTPLPS
70 80 90 100 110 120
RGDSGQSPIV RPAPSASKEV KYEESSRKQD SGQSGSRPLR DKDSQVRPSG DSSYPVSRSP
130 140 150 160 170 180
FQKEDSNIIV SRPTQRPVRP NPGGSYQGNR GPGQGGGYQG NRGPGQGGGY QGNRGPGQQT
190 200 210 220 230 240
GPGNRFGGSG PGNRSGGPGG RPMPITSAEV ELSQARGSTG ASKKKGHDKE KTSSDKRDFS
250 260 270 280 290 300
GAENTKFFKQ RFKKTKVVGV SGVSVPKEIT VLENVQVGEL AKKMNLKPGD VIGKLMKMGM
310 320 330 340 350 360
MVTINNIIDA ETAALLADEY GCKVKVVSLY EETIIEEEKD NEGDYINRPP VVTIMGHVDH
370 380 390 400 410 420
GKTKLLDTIR RSSVIDTESG GITQHIGAYQ VKTARGLITF LDTPGHEAFT SMRARGAKVT
430 440 450 460 470 480
DIVILVVAAD DGVMPQTLEA ISHAKAAEVP IIVAINKIDL PTANPDKIMQ ELANHGLQSE
490 500 510 520 530 540
EWGGQTMYVK ISARENIGID KLLEVILLQA EVMDLKANPK RKAKGTIIEA KLDPGRGSVA
550 560 570 580 590 600
TVLIQNGTLR VGDPFVAGVF SGRVRAMYND LGQLIEEAGP AFPAQVTGID GVPDAGAPFD
610 620 630 640 650 660
AMADEKEARN ISQHRIEFEK IGNAGAAAGT TSKVTLENMN EYIKLGALKE LKVIIKADVR
670 680 690 700 710 720
GSAEAIKESL EKLSTPEVKL NVIQSGAGAI VDMDVMLASA SNALIIGFHV RANPKTIALA
730 740 750 760 770 780
EKEQVQIKYY NIIYQVVDEI KLAMEGLLEP EKIEEVIGTA EIREIFKVSK IGNIAGCMVT
790 800 810 820 830 840
SGKIQKSANV RVISDGVTKF DGKLKSLKRV KDDVNDVVSG FECGIQVDGY NDFKVGDTIE
850
AYNVTVIKRK LE