Q04I77

PR
Gene name
dapH
Protein name
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase
Names
Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase
Species
Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
KEGG Pathway
spd:SPD_1923
EC number
2.3.1.89: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

188-232 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q04I77

Entry ID Method Resolution Chain Position Source
AF-Q04I77-F1 Predicted AlphaFoldDB

No variants for Q04I77

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q04I77

No associated diseases with Q04I77

5 regional properties for Q04I77

Type Name Position InterPro Accession
repeat Hexapeptide repeat 100 - 114 IPR001451-1
repeat Hexapeptide repeat 118 - 152 IPR001451-2
repeat Hexapeptide repeat 161 - 196 IPR001451-3
domain 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal 6 - 82 IPR013710
conserved_site Hexapeptide transferase, conserved site 170 - 198 IPR018357

Functions

Description
EC Number 2.3.1.89 Transferring groups other than amino-acyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
tetrahydrodipicolinate N-acetyltransferase activity Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H(2)O = L-2-acetamido-6-oxopimelate + CoA.

2 GO annotations of biological process

Name Definition
diaminopimelate biosynthetic process The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
lysine biosynthetic process via diaminopimelate The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTATKMNAQE IIQFIANAEK KTSVKVTFEG QLATAVPSSV VKLGNVLFGD WKDVAPLLEG
70 80 90 100 110 120
LVENQDYVVE QDARNSAVPL LDKRAINARI EPGAIIRDQV EIGDNAVIMM GAVINIGAEI
130 140 150 160 170 180
GAGTMIDMGA ILGGRAIVGK NSHVGAGAVL AGVIEPASAE PVRVGDNVLI GANAVVIEGV
190 200 210 220 230
QIGSGSVVAA GAIVTQDVPE NVVVAGVPAR IIKEIDAQTQ QKTALEDALR TL