Q04AU8

PR
Gene name
fabH
Protein name
Beta-ketoacyl-[acyl-carrier-protein] synthase III
Names
Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III
Species
Lactobacillus delbrueckii subsp bulgaricus (strain ATCC BAA-365 / Lb-18)
KEGG Pathway
lbu:LBUL_0818
EC number
2.3.1.180: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-84 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q04AU8

Entry ID Method Resolution Chain Position Source
AF-Q04AU8-F1 Predicted AlphaFoldDB

No variants for Q04AU8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q04AU8

No associated diseases with Q04AU8

10 regional properties for Q04AU8

Type Name Position InterPro Accession
conserved_site Quinoprotein dehydrogenase, conserved site 51 - 79 IPR001479-1
conserved_site Quinoprotein dehydrogenase, conserved site 282 - 303 IPR001479-2
repeat Pyrrolo-quinoline quinone repeat 82 - 278 IPR002372-1
repeat Pyrrolo-quinoline quinone repeat 532 - 568 IPR002372-2
repeat Pyrrolo-quinoline quinone beta-propeller repeat 97 - 129 IPR018391-1
repeat Pyrrolo-quinoline quinone beta-propeller repeat 147 - 178 IPR018391-2
repeat Pyrrolo-quinoline quinone beta-propeller repeat 192 - 235 IPR018391-3
repeat Pyrrolo-quinoline quinone beta-propeller repeat 361 - 397 IPR018391-4
repeat Pyrrolo-quinoline quinone beta-propeller repeat 452 - 517 IPR018391-5
repeat Pyrrolo-quinoline quinone beta-propeller repeat 527 - 558 IPR018391-6

Functions

Description
EC Number 2.3.1.180 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
3-oxoacyl-[acyl-carrier-protein] synthase activity Catalysis of the reaction: acyl-
beta-ketoacyl-acyl-carrier-protein synthase III activity Catalysis of the reaction: acetyl-CoA + malonyl-

1 GO annotations of biological process

Name Definition
fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTYARIAKSS RYLPEFAVSN DDLSQIMETS DEWIKTRTGI SSRRISQQEN TSDLAIQVAK
70 80 90 100 110 120
QLLAGEDPAG VDLIIVATMS PDAYTPATAA LVQAAVGAEN AACFDLSAAC SGFVYALDVA
130 140 150 160 170 180
EKMLRRPGGM ALVIGAETLS KLVDWQDRTT AVLFGDGAGG VLVKNDALEP HFLASQLKSY
190 200 210 220 230 240
GHLAKFLSAG QTSPQPFPGP VTDLAPFKMN GREVYKFATH KVPEVITACL EEAGVGLAEV
250 260 270 280 290 300
DLFLFHQANY RIVKQVARRL DLPEEKFPCN IAEYGNTSAA SEAILLAELA EEGKAQAGDL
310
VVLAGFGGGL TAAAQLVRL