Q049W4

PR
Gene name
hrcA
Protein name
Heat-inducible transcription repressor HrcA
Names
Species
Lactobacillus delbrueckii subsp bulgaricus (strain ATCC BAA-365 / Lb-18)
KEGG Pathway
lbu:LBUL_1229
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-94 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q049W4

Entry ID Method Resolution Chain Position Source
AF-Q049W4-F1 Predicted AlphaFoldDB

No variants for Q049W4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q049W4

No associated diseases with Q049W4

2 regional properties for Q049W4

Type Name Position InterPro Accession
domain Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain 1 - 71 IPR005104
domain Heat-inducible transcription repressor HrcA, C-terminal 104 - 325 IPR021153

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

1 GO annotations of biological process

Name Definition
negative regulation of DNA-templated transcription Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLTKRQELIL KTIIQDFTKT HEPVGSKTVM NQLSIKVSSA TIRNEMAVLE EHGLIEKTHS
70 80 90 100 110 120
SSGRVPSTEG YRYYLDNLVQ PLQLPEEMYN QIGYQFDQPF NQVDEIVKEA ARILSDLTDY
130 140 150 160 170 180
TAFAEGPEDK NVSITGFRIV PLAPRQVMAI LVISDGSVKN QLYTLPRHIS GDEVEQAARL
190 200 210 220 230 240
INDQLVGKNL SEINKQTFEQ LYSSQIVGKN APEFLELLES VIKDAASEQM YVDGQLNLLN
250 260 270 280 290 300
NIENSDLKAI KSLYELINSS SLAGELIDLS DSPSHYPVHV RLGAELENDL LKDFSLVMAE
310 320 330 340
YSVGRYGRGT IALLGPRHMP YSEMIGLMEY FRQELARKLL DYYGRFK