Q04850

PR
Gene name
ntrY (AZC_3084)
Protein name
Nitrogen regulation protein NtrY
Names
Species
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)
KEGG Pathway
azc:AZC_3084
EC number
2.7.13.3: Protein-histidine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

694-771 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q04850

Entry ID Method Resolution Chain Position Source
AF-Q04850-F1 Predicted AlphaFoldDB

No variants for Q04850

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q04850

No associated diseases with Q04850

7 regional properties for Q04850

Type Name Position InterPro Accession
domain PAS domain 7 - 103 IPR000014
domain Histidine kinase/HSP90-like ATPase 233 - 348 IPR003594
domain Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 129 - 194 IPR003661
domain Signal transduction histidine kinase-related protein, C-terminal 281 - 295 IPR004358-1
domain Signal transduction histidine kinase-related protein, C-terminal 310 - 328 IPR004358-2
domain Signal transduction histidine kinase-related protein, C-terminal 333 - 346 IPR004358-3
domain Histidine kinase domain 136 - 348 IPR005467

Functions

Description
EC Number 2.7.13.3 Protein-histidine kinases
Subcellular Localization
  • Cell membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
phosphorelay sensor kinase activity Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.

2 GO annotations of biological process

Name Definition
nitrogen fixation The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTQAAFDQAS DNGPMTPSGS SFGLFAPAVV LLALISALAT FLILMGLTPV VPTHQVVISV
70 80 90 100 110 120
LLVNAAAVLI LSAMVGREIW RIAKARARGR AAARLHIRIV GLFAVVSVVP AILVAVVASL
130 140 150 160 170 180
TLDRGLDRWF SMRTQEIVAS SVSVAQTYVR EHALNIRGDI LAMSADLTRL KSVYEGDRSR
190 200 210 220 230 240
FNQILTAQAA LRNLPGAMLI RRDLSVVERA NVNIGREFIV PANLAIGDAT PDQPVIYLPN
250 260 270 280 290 300
DADYVAAVVP LKDYDDLYLY VARLIDPRVI GYLKTTQETL ADYRSLEERR FGVQVAFALM
310 320 330 340 350 360
YAVITLIVLL SAVWLGLNFS KWLVAPIRRL MSAADHVAEG NLDVRVPIYR AEGDLASLAE
370 380 390 400 410 420
TFNKMTHELR SQREAILTAR DQIDSRRRFT EAVLSGVGAG VIGLDSQERI TILNRSAERL
430 440 450 460 470 480
LGLSEVEALH RHLAEVVPET AGLLEEAEHA RQRSVQGNIT LTRDGRERVF AVRVTTEQSP
490 500 510 520 530 540
EAEHGWVVTL DDITELISAQ RTSAWADVAR RIAHEIKNPL TPIQLSAERL KRKFGRHVTQ
550 560 570 580 590 600
DREIFDQCTD TIIRQVGDIG RMVDEFSSFA RMPKPVVDSQ DMSEIIRQTV FLMRVGHPEV
610 620 630 640 650 660
VFDSEVPPAM PARFDRRLVS QALTNILKNA AEAIEAVPPD VRGQGRIRVS ANRVGEDLVI
670 680 690 700 710 720
DIIDNGTGLP QESRNRLLEP YVTTREKGTG LGLAIVGKIM EEHGGGIELN DAPEGRGAWI
730 740 750 760 770
RLTLKAEGPK AEPTDASTKA TGAATPAAPA ASAMARDAAA DSAARGKNER T