Q04845

PR
Gene name
cfrBIM
Protein name
Type II methyltransferase M.CfrBI
Names
M.CfrBI, Modification methylase CfrBI, N(4)- cytosine-specific methyltransferase CfrBI
Species
Citrobacter freundii
KEGG Pathway
EC number
2.1.1.113: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

50-127 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q04845

Entry ID Method Resolution Chain Position Source
AF-Q04845-F1 Predicted AlphaFoldDB

No variants for Q04845

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q04845

No associated diseases with Q04845

2 regional properties for Q04845

Type Name Position InterPro Accession
domain DNA methylase N-4/N-6 132 - 363 IPR002941
conserved_site DNA methylase, N-4 cytosine-specific, conserved site 136 - 141 IPR017985

Functions

Description
EC Number 2.1.1.113 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
N-methyltransferase activity Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule.
site-specific DNA-methyltransferase (cytosine-N4-specific) activity Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.

1 GO annotations of biological process

Name Definition
DNA restriction-modification system A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTVKNNYLNR GYLVTSTTQA KKIAKLHLEK LDLADKFSFG LPEVDDRYHV WRVPLVATGH
70 80 90 100 110 120
RIGEIVINSK TSTIDYKKSS KSPFLIKKAM EVVHTPKKVK KEKKIISKSP LNNMLLQGNC
130 140 150 160 170 180
AETLKKLPDE SVNLVFTSPP YYNAKPEYSE YHTYDEYLSL LRSVIKECHR VLSEGRFFVI
190 200 210 220 230 240
NVSPVLIRRA SRNEASKRIA VPFDLHRLFI EEGYEFIDDI HWVKPEGAGW ALGRGRRFAA
250 260 270 280 290 300
DRNPLQYKPV PVTEYILVYR KKTDKLIDWN IRNHHSKEDV FDSKIGDDYE KTNLWKINPS
310 320 330 340 350 360
RNRKHPATFP YGLAERVIKY YSFKNDVILD PFAGSGTTAK AAIDLGRRFV MCEISKQYID
370
LIIEGTMLGG DLKIIN