Q04468
Gene name |
CYP73A1 |
Protein name |
Trans-cinnamate 4-monooxygenase |
Names |
Cinnamic acid 4-hydroxylase, C4H, CA4H, Cytochrome P450 73, Cytochrome P450C4H |
Species |
Helianthus tuberosus (Jerusalem artichoke) (Helianthus tomentosus) |
KEGG Pathway |
|
EC number |
1.14.14.91: With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q04468
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q04468-F1 | Predicted | AlphaFoldDB |
No variants for Q04468
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q04468 | |||||
No associated diseases with Q04468
1 regional properties for Q04468
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Cytochrome P450, conserved site | 440 - 449 | IPR017972 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.14.91 | With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| iron ion binding | Binding to an iron (Fe) ion. |
| trans-cinnamate 4-monooxygenase activity | Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| sesquiterpene biosynthetic process | The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDLLLIEKTL | VALFAAIIGA | ILISKLRGKK | FKLPPGPIPV | PIFGNWLQVG | DDLNHRNLTD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LAKRFGEILL | LRMGQRNLVV | VSSPELAKEV | LHTQGVEFGS | RTRNVVFDIF | TGKGQDMVFT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VYGEHWRKMR | RIMTVPFFTN | KVVQQYRYGW | EAEAAAVVDD | VKKNPAAATE | GIVIRRRLQL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MMYNNMFRIM | FDRRFESEDD | PLFLKLKALN | GERSRLAQSF | EYNYGDFIPI | LRPFLRNYLK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LCKEVKDKRI | QLFKDYFVDE | RKKIGSTKKM | DNNQLKCAID | HILEAKEKGE | INEDNVLYIV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ENINVAAIET | TLWSIEWGIA | ELVNHPEIQA | KLRHELDTKL | GPGVQITEPD | VQNLPYLQAV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VKETLRLRMA | IPLLVPHMNL | HDAKLGGFDI | PAESKILVNA | WWLANNPDQW | KKPEEFRPER |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FLEEEAKVEA | NGNDFRYLPF | GVGRRSCPGI | ILALPILGIT | IGRLVQNFEL | LPPPGQSKID |
| 490 | 500 | ||||
| TDEKGGQFSL | HILKHSTIVA | KPRSF |