Q03W71

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y)
KEGG Pathway
lme:LEUM_1458
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

388-460 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q03W71

Entry ID Method Resolution Chain Position Source
AF-Q03W71-F1 Predicted AlphaFoldDB

No variants for Q03W71

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q03W71

No associated diseases with Q03W71

3 regional properties for Q03W71

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 277 - 286 IPR020557
domain Fumarate lyase, N-terminal 8 - 299 IPR022761
domain Argininosuccinate lyase, C-terminal 365 - 433 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDKLWGGRF TAKAAEWVDE FGASIHFDQK MAAEDIEGSI AHAKMLGKQG IISPEESEKI
70 80 90 100 110 120
VSGLKIINEE LIAGKIEFDV KNEDIHMNIE SLLTEKIGPV AGKLHTARSR NDQVATDFHL
130 140 150 160 170 180
WVKHRLPHVL ESLTELQEEL LTLATTHAGT IMSGYTHLQH AQPITYGHYL LAYFEMFQRD
190 200 210 220 230 240
YERFEFNQKH TDILPLGAAA LAGTTFPIDR EFVASELGFD SIYHNSLDAV SDRDFALEFL
250 260 270 280 290 300
SNAAILMMHL SRMAEELILW STYEFNYIEL SDDFSTGSSI MPQKKNADFA ELVRGKTGRS
310 320 330 340 350 360
YGALMGLLTT MKSLPLAYNK DMQEDKEQVF DIMDTVLASV KVFTGMLSGL TVHKERMLAT
370 380 390 400 410 420
TQDDFSNATE LADYLATKGV PFREAHAIVG QLVLTGIQSK TPLQKMSLSD LQAVAPQIEE
430 440 450
DIYDKLQSET AVNRRTSLGG TAVENVKKEI VRNKKVLEAR