Q03NG2

PR
Gene name
ptcA
Protein name
Putrescine carbamoyltransferase
Names
PTC, PTCase, Putrescine transcarbamoylase, Putrescine transcarbamylase
Species
Levilactobacillus brevis (strain ATCC 367 / BCRC 12310 / CIP 105137 / JCM 1170 / LMG 11437 / NCIMB 947 / NCTC 947) (Lactobacillus brevis)
KEGG Pathway
lbr:LVIS_2210
EC number
2.1.3.6: Carboxy- and carbamoyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

27-112 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q03NG2

Entry ID Method Resolution Chain Position Source
AF-Q03NG2-F1 Predicted AlphaFoldDB

No variants for Q03NG2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q03NG2

No associated diseases with Q03NG2

2 regional properties for Q03NG2

Type Name Position InterPro Accession
domain Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain 154 - 309 IPR006131
domain Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding 4 - 144 IPR006132

Functions

Description
EC Number 2.1.3.6 Carboxy- and carbamoyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
amino acid binding Binding to an amino acid, organic acids containing one or more amino substituents.
ornithine carbamoyltransferase activity Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
putrescine carbamoyltransferase activity Catalysis of the reaction: carbamoyl phosphate + putrescine = N-carbamoylputrescine + H(+) + phosphate.

1 GO annotations of biological process

Name Definition
putrescine biosynthetic process from arginine via N-carbamoylputrescine The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine, via the intermediate N-carbamoylputrescine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in two single enzymatic steps.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTKRDFIDTN TYTKEEIQYM IDLGIKIKES IKNGYYPPLL KNKTLGMIFE QSSTRTRTSA
70 80 90 100 110 120
EAAMTELGGH AQYLAPGQIQ LGGHETIEDT SQVLGRILDI IGARVERHHT VAEVGKFAKV
130 140 150 160 170 180
PVVNFMSDYN HPTQELGDII TMTEHLPKGK KLSDCKIVFV GDATQVCVST MFMATKMGMD
190 200 210 220 230 240
FVQFGPKGFQ IKPETLKIGQ QNAKVSGGSV TITEDADEAF KDADFIYTDV WYGLYEAELS
250 260 270 280 290 300
EEDRMKIFYP KYQVNAELVA KASDHVKFMH CLPATRGEEV TDEVIDSDYS IVWDEAENRK
310 320 330 340
TAMRAIFVYL LNPELRKAQA SQAVADKYDA EFSLMLRNAV DDQRNAD