Q03JS8
Gene name |
galK |
Protein name |
Galactokinase |
Names |
Galactose kinase |
Species |
Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9) |
KEGG Pathway |
ste:STER_1371 |
EC number |
2.7.1.6: Phosphotransferases with an alcohol group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q03JS8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q03JS8-F1 | Predicted | AlphaFoldDB |
No variants for Q03JS8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q03JS8 | |||||
No associated diseases with Q03JS8
5 regional properties for Q03JS8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | GHMP kinase, ATP-binding, conserved site | 121 - 132 | IPR006203 |
| domain | GHMP kinase N-terminal domain | 114 - 181 | IPR006204 |
| domain | GHMP kinase, C-terminal domain | 284 - 366 | IPR013750 |
| domain | Galactokinase, N-terminal domain | 8 - 57 | IPR019539 |
| conserved_site | Galactokinase, conserved site | 26 - 37 | IPR019741 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.1.6 | Phosphotransferases with an alcohol group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| galactokinase activity | Catalysis of the reaction: D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + 2 H(+). |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| galactose metabolic process | The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNTSQLREKF | KEVFGVEADH | TFFSPGRINL | IGEHTDYNGG | NVLPVAITLG | TYGAARKRDD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KVLRFFSANF | EEKGIIEVPL | ENLRFENEHN | WTNYPKGVLH | FLQEAGHTID | SGMDIYIYGN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IPNGSGLSSS | SSLELLIGVI | VEKLYDLKLE | RLDLVKIGKQ | TENDFIGVNS | GIMDQFAIGM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GADQCAIYLD | TNTLKYDLVP | LDLKDNVVVI | MNTNKRRELS | DSKYNERRAE | CETAVSELQE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KLDIQTLGEL | DLWTFDAYSY | LIKDENRIKR | ARHAVLENQR | TLQARKALEA | GELEGFGRLM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NASHVSLKYD | YEVTGLELDT | LAHTAWEQEG | VLGARMTGAG | FGGCAIALVN | KDKVEDFKKA |
| 370 | 380 | ||||
| VGQRYEEVVG | YAPSFYIAEV | TGGSRVLD |