Q03976

PR
Gene name
RSM24 (YDR175C)
Protein name
37S ribosomal protein S24, mitochondrial
Names
Mitochondrial ribosomal small subunit protein 24, Mitochondrial small ribosomal subunit protein mS35
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YDR175C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-229 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

9 structures for Q03976

Entry ID Method Resolution Chain Position Source
5MRC EM 325 A YY 47-319 PDB
5MRE EM 375 A YY 47-319 PDB
5MRF EM 497 A YY 47-319 PDB
8D8K EM 313 A Y 1-319 PDB
8D8L EM 260 A Y 1-319 PDB
8OM2 EM 257 A Y 1-319 PDB
8OM3 EM 287 A Y 1-319 PDB
8OM4 EM 232 A Y 1-319 PDB
AF-Q03976-F1 Predicted AlphaFoldDB

3 variants for Q03976

Variant ID(s) Position Change Description Diseaes Association Provenance
s04-814091 20 K>R No SGRP
s04-814016 45 A>V No SGRP
s04-813264 296 E>K No SGRP

No associated diseases with Q03976

1 regional properties for Q03976

Type Name Position InterPro Accession
domain Ribosomal protein S24/S35, mitochondrial, conserved domain 171 - 299 IPR019349

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
  • Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrial small ribosomal subunit The smaller of the two subunits of a mitochondrial ribosome.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name Definition
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
mitochondrial translation The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKVPLGLWKV SRGNLWSTQK RVLTMSRCLN SDAGNEAKTV REGPAFSADL YMHPEKWKGL
70 80 90 100 110 120
PPQRILELYW ERMARLGSEY KPNKDELNAL LTTSEYSNVP VNDIKKLYHR GEQGAIDIKG
130 140 150 160 170 180
GNVNRDNSLR PFMFDELPSQ AQELVAQHRE QRFYNRLAAY ELPLLAQYRQ EYKRPSPESH
190 200 210 220 230 240
PVTYRYTSYV GEEHPNSRKV VLSVKTKELG LEEKSLHKFR ILARSRYDHT TDIFKMSSDK
250 260 270 280 290 300
FEHASQNARY LHDILQRLLA ESKDLTEDDF SDVPLDTRHT IAKSLRKKKR DYEFPEHWKR
310
PEDAPKKKFD IVDQLLSTL