AiPD: Autoinhibited Protein Database

Gene name	WAR1 (YML076C)
Protein name	Weak acid resistance protein 1
Names
Species	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway	sce:YML076C
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-88 (Predicted disordered autoinhibitory region) PR

1-88 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q03631-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
s13-115325	8	T>I	No	SGRP
s13-115316	11	A>V	No	SGRP
s13-115293	19	D>N	No	SGRP
s13-115244	35	P>Q	No	SGRP
s13-114963	129	P>S	No	SGRP
s13-114933	139	T>A	No	SGRP
s13-114707	214	N>S	No	SGRP
s13-114648	234	D>N	No	SGRP
s13-114545	268	F>S	No	SGRP
s13-114474	292	Y>D	No	SGRP
s13-114474	292	Y>N	No	SGRP
s13-114470	293	S>C	No	SGRP
s13-114297	351	I>V	No	SGRP
s13-113864	495	K>R	No	SGRP
s13-113729	540	A>V	No	SGRP
s13-113691	553	H>N	No	SGRP
s13-113135	738	A>G	No	SGRP
s13-113088	754	Y>H	No	SGRP
s13-113072	759	S>F	No	SGRP
s13-112781	856	A>V	No	SGRP
s13-112754	865	T>S	No	SGRP
s13-112670	893	D>G	No	SGRP

Type	Name	Position	InterPro Accession
domain	Zn(2)Cys(6) fungal-type DNA-binding domain	70 - 120	IPR001138

		Description
EC Number
Subcellular Localization	Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
DNA-binding transcription factor activity	A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
DNA-binding transcription factor activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
sequence-specific DNA binding	Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
zinc ion binding	Binding to a zinc ion (Zn).

Name	Definition
positive regulation of transcription by RNA polymerase II	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins