Q03305

PR
Gene name
RMT2
Protein name
Protein arginine N-methyltransferase 2
Names
Protein-arginine N5-methyltransferase, Type IV protein arginine N-methyltransferase, Type IV PRMT
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YDR465C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

132-214 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q03305

Entry ID Method Resolution Chain Position Source
AF-Q03305-F1 Predicted AlphaFoldDB

10 variants for Q03305

Variant ID(s) Position Change Description Diseaes Association Provenance
s04-1394419 50 N>D No SGRP
s04-1394079 163 G>D No SGRP
s04-1394029 180 E>K No SGRP
s04-1394010 186 D>G No SGRP
s04-1393956 204 K>T No SGRP
s04-1393921 216 G>S No SGRP
s04-1393909 220 D>Y No SGRP
s04-1393885 228 L>V No SGRP
s04-1393583 328 I>M No SGRP
s04-1393522 349 N>H No SGRP

No associated diseases with Q03305

1 regional properties for Q03305

Type Name Position InterPro Accession
domain CRIB domain 98 - 133 IPR000095

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
  • Appears often very close to the nuclear membrane and the nuclear pores
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
protein-arginine N5-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. The reaction is S-adenosyl-L-methionine
S-adenosylmethionine-dependent methyltransferase activity +Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

1 GO annotations of biological process

Name Definition
peptidyl-arginine methylation The addition of a methyl group to an arginine residue in a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSELHALLTF PERPISQSYY VPKLQHFLKS GIPATYTLEQ VAAFEHEEKN RNGDKEFRES
70 80 90 100 110 120
TDDNKTSNTT PLHVLARSLP LDIKDEELQV VMDMMNILFE YGAGWNFIDY EDKTVGDLFL
130 140 150 160 170 180
ERNQSRESPL YRRLVEAGVS AELLLRKLNG GDVEFLDTDE LIGIEPEESV QTAVDGQKEE
190 200 210 220 230 240
SVGSDDDATA ANQQVYLKTE LEYKDDALIT KENKDGVMMD WETKIMELAS ETLFPDPEAT
250 260 270 280 290 300
NSATILNIGF GMGIIDTFIQ ARKPYRHYIC EAHPDVLAKM KMDGWYEKDN VVILEGRWQD
310 320 330 340 350 360
TLNNLLDKGE VFFDGIYYDT FSEHYQDILD LYDVVVGLIK PEGVFSFFNG LGADRSLCYD
370 380 390 400 410
VYKEIVEIDV ATYGMKCDYT RYSLDEQLPD WNDVKRSYFN CNYYYHPRIT FA