Q03279
Gene name |
|
Protein name |
Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 |
Names |
Retrovirus-related Pol polyprotein from type I retrotransposable element R2 |
Species |
Bradysia coprophila (Dark-winged fungus gnat) (Sciara coprophila) |
KEGG Pathway |
|
EC number |
2.7.7.49: Nucleotidyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q03279
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q03279-F1 | Predicted | AlphaFoldDB |
No variants for Q03279
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q03279 | |||||
No associated diseases with Q03279
1 regional properties for Q03279
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Reverse transcriptase domain | 199 - 475 | IPR000477 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.7.49 | Nucleotidyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| endonuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. |
| RNA-directed DNA polymerase activity | Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| VSVPPTSYRD | RIMNALEESM | IDVDAIRGSS | ARELVEIGKV | ALLNQPMDEG | RIMSWLSDRF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PDTQKPKGPI | YSKTTIYHGT | NKQKRKQRYA | LVQSLYKKDI | SAAARVVLDE | NDKIATKIPP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VRHMFDYWKD | VFATGGGSAA | TNINRAPPAP | HMETLWDPVS | LIEIKSARAS | NEKGAGPDGV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TPRSWNALDD | RYKRLLYNIF | VFYGRVPSPI | KGSRTVFTPK | IEGGPDPGVF | RPLSICSVIL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| REFNKILARR | FVSCYTYDER | QTAYLPIDGV | CINVSMLTAI | IAEAKRLRKE | LHIAILDLVK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AFNSVYHSAL | IDAITEAGCP | PGVVDYIADM | YNNVITEMQF | EGKCELASIL | AGVYQGDPLS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GPLFTLAYEK | ALRALNNEGR | FDIADVRVNA | SAYSDDGLLL | AMTVIGLQHN | LDKFGETLAK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IGLRINSRKS | KTVSLVPSGR | EKKMKIVSNR | RLLLKASELK | PLTISDLWKY | LGVVYTTSGP |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EVAKVSMDDD | LSKLTKGPLK | PQQRIHLLKT | FVIPKHLNRL | VLSRTTATGL | CKMDLLIRKY |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VRRWLRLPGD | VPVAFLYAPV | KAGGKGIPCL | KQWIPLMRFL | RLNKAKRTGG | DRIAAVLNCQ |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LYASISHSCK | TGPVSVGLWR | STNTGGLSAY | WRRILIGMVD | GKDLKSAQNH | SSATSFNSIR |
| 670 | 680 | 690 | 700 | 710 | 720 |
| MNDISGEDYI | HYNQLRTNSI | PTRKRTARGR | PNKPTACRAG | CDKLKRLQHD | IQGCIRSQGG |
| 730 | 740 | 750 | 760 | 770 | 780 |
| LVQRHDRVVD | LLFDECETKG | YAAEKVVHLR | TSEELWKPDL | VLKKNGRVVV | VDAQVVQCGR |
| 790 | 800 | 810 | 820 | 830 | 840 |
| LESDHRVKVS | KYRDDPELAD | VIREKYAVQE | VTFEACTLSY | KGIWSKNSVE | GLQKLGISNY |
| 850 | 860 | ||||
| CLFKIVTSVL | RGSWLNWVRF | NNVTTVVHW |