Q03277

PR
Gene name
Protein name
Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1
Names
Retrovirus-related Pol polyprotein from type I retrotransposable element R1
Species
Bradysia coprophila (Dark-winged fungus gnat) (Sciara coprophila)
KEGG Pathway
EC number
2.7.7.49: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

359-445 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q03277

Entry ID Method Resolution Chain Position Source
AF-Q03277-F1 Predicted AlphaFoldDB

No variants for Q03277

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q03277

No associated diseases with Q03277

2 regional properties for Q03277

Type Name Position InterPro Accession
domain Multicopper oxidase, C-terminal 377 - 510 IPR011706
domain Multicopper oxidase, N-terminal 87 - 197 IPR011707

Functions

Description
EC Number 2.7.7.49 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
RNA-directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
LRGEVRGLPS SFRVVTSRIV NDGIGISAIV INDPEADVLV IEDCTDEYGV CVLIKGATCS
70 80 90 100 110 120
MYVVSVYCRF GTALGPYLQY MENVRVKCGN TYMIMGMDAN AVSPLWFSKG ENLGRGRLNE
130 140 150 160 170 180
ANGLLLEEWI LEGRMIVINE PSEWYTFSGP NGSSDIDVTL VNEAGGRFGY EWSVQPEWGV
190 200 210 220 230 240
SDHNLIRIRV SLDGLVADAS PSPQSARWQT RDTDWGEYMG DVKAKADVFG LAQYENVSVD
250 260 270 280 290 300
EKVDLLTEWI YGANDWNMRR HTAVRTFQNE WWSVELAEKR SELRRRRHAF QRIRNAGAAS
310 320 330 340 350 360
LADRLQAFRD CKIEYKRMLC EAKLRCWQEF VASESNENPW GRVFKLCRGR RKPVDVCSVK
370 380 390 400 410 420
VDGVYTDTWE GSVNAMMNVF FPASIDDASE IDRLKAIARP LPPDLEMDEV SDSVRRCKVR
430 440 450 460 470 480
KSPGPDGIVG EMVRAVWGAI PEYMFCLYKQ CLLESYFPQK WKIASLVILL KLLDRIRSDP
490 500 510 520 530 540
GSYRPICLLD NLGKVLEGIM VKRLDQKLMD VEVSPYQFAF TYGKSTEDAW RCVQRHVECS
550 560 570 580 590 600
EMKYVIGLNI DFQGAFDNLG WLSMLLKLDE AQSNEFGLWM SYFGGRKVYY VGKTGIVRKD
610 620 630 640 650 660
VTRGCPQGSK SGPAMWKLVM NELLLALVAA GFFIVAFADD GTIVIGANSR SALEELGTRC
670 680 690 700 710 720
LQLCHEWGKR VCVPVSAGKT TCILMKGHLS ANRPPCIRLN GTSISYKSEV KHLGIFVAER
730 740 750 760 770 780
MNFRPHFVYL RGKILGLVGC LRRVMRKSWG LGRRATCILY KGLFVACMSY GASVWFRTLR
790 800 810 820 830 840
FSYASILLNR CQRLVLYASL NVCRTVSTER MQVLHGELPW DLEATRRGLL SEFRKGITPV
850 860 870 880 890 900
DGDPITDEEM LGLSGSQFKE LLMERLLDVW QGRWDVSEKG RLTHEFIPSV RFVRENEWMA
910 920 930 940 950 960
FGLCLGYVLT GHGSMNGFLH KRGLSNTPVC MCGAPNEDVK HLLGECPLYE DLRDLNGCGL
970 980 990 1000
LIRNGSLDVS GALSEIGAFE KLNQFAVSLF GRRSRLMRGM RIRE