Q03153

PR
Gene name
ATP25 (YMR098C, YM6543.05C)
Protein name
ATPase synthesis protein 25, mitochondrial
Names
OLI1 mRNA stabilization factor
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YMR098C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

10-87 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q03153

Entry ID Method Resolution Chain Position Source
AF-Q03153-F1 Predicted AlphaFoldDB

12 variants for Q03153

Variant ID(s) Position Change Description Diseaes Association Provenance
s13-462534 25 F>L No SGRP
s13-462520 30 Y>C No SGRP
s13-462192 139 L>F No SGRP
s13-462097 171 S>N No SGRP
s13-461815 265 T>N No SGRP
s13-461566 348 R>K No SGRP
s13-461497 371 S>W No SGRP
s13-461377 411 Q>R No SGRP
s13-461365 415 R>K No SGRP
s13-461231 460 D>N No SGRP
s13-461206 468 V>E No SGRP
s13-460783 609 T>K No SGRP

No associated diseases with Q03153

1 regional properties for Q03153

Type Name Position InterPro Accession
domain ATP25 mRNA stabilisation domain 305 - 594 IPR025210

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
mitochondrial gene expression The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
mitochondrial proton-transporting ATP synthase complex assembly The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane.
mRNA stabilization Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNKFCLLPFH GKRIGVANIP FTILFKKGPY FLHSHITAVY YSTKGKNDSH EQSRVSKKST
70 80 90 100 110 120
FTPLETPWYL RIVDNEKELM EGKKNNHHTM NKELEIPKTS PNSLRKIADL LTGKLGLDDF
130 140 150 160 170 180
LVFDLRKKSP NSVSAVNKLG DFMVICTARS TKHCHKSFLE LNKFLKHEFC SSAYVEGNFN
190 200 210 220 230 240
ERQESRRKRR LARKSNLSKL LGRSSECSAK DLNSEAWYMI DCRVDGIFVN ILTQRRRNEL
250 260 270 280 290 300
NLEELYAPEN EKSKFQNIDS GNVPTISGVN EISSNNNILL GLRRLAQQRR RYSTINPNGL
310 320 330 340 350 360
SNLRYFLQKE DFKGANKIIQ SSSGTETHNI RTLEHVKNTL KDLVGQERKV DVVQWKSLFD
370 380 390 400 410 420
EHSTFLTINQ SAAYWPLRLE YAILLNKADP QFYSDRVFLK DYLLLKKSLG QELIREDLIA
430 440 450 460 470 480
LLEMVLKTQH SSHSYFNLVK QNRVIIRALN LFKGLQTEDD GSVVYDEVVI SLLLNSMVAD
490 500 510 520 530 540
ERVKLRSLYE TIDHIFQTFG DKLTSGMIVS ILQNLAKIKD WNKLLQVWEA ITPTEGEGQD
550 560 570 580 590 600
KRPWNEFINV INQSGDSHVI SKIVNNGHLL WIRRLNVNVT PELCNSIKAL LKTAGMENST
610
LEEFLVRGTN NQ