Q03025

PR
Gene name
aprE (PA1247)
Protein name
Alkaline protease secretion protein AprE
Names
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG Pathway
pae:PA1247
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

90-294 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q03025

Entry ID Method Resolution Chain Position Source
AF-Q03025-F1 Predicted AlphaFoldDB

No variants for Q03025

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q03025

No associated diseases with Q03025

2 regional properties for Q03025

Type Name Position InterPro Accession
conserved_site Secretion protein HlyD, conserved site 396 - 418 IPR006144
domain Cation efflux system protein CusB, domain 1 23 - 388 IPR043602

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
protein secretion The controlled release of proteins from a cell.
secretion The controlled release of a substance by a cell or a tissue.
transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTRTVKRDEN AYARLGWLLV LFGFGGALLW AAFAPLDQGV AVPATVIISG QRKSVQHPLG
70 80 90 100 110 120
GVVKHILVRD GQHVEAGEPL IRMEPTQARA NVDSLLNRYA NARLNQARLQ AEYDGRRTLE
130 140 150 160 170 180
MPAGLAEQAP LPTLGERLEL QRQLLHSRQT ALANELSALR ANIEGLRAQL EGLRQTEGNQ
190 200 210 220 230 240
RLQQRLLNSQ LSGARDLAEE GYMPRNQLLE QERQLAEVNA RLSESSGRFG QIRQSIAEAQ
250 260 270 280 290 300
MRIAQREEEY RKEVNGQLAE TQVNARTLWE ELSSARYELR HAEIRAPVSG YVAGLKVFTD
310 320 330 340 350 360
GGVIGPGELL MYIVPNSDSL EVEGQLAVNL VDRIHSGLPV EMLFTAFNQS KTPRVTGEVT
370 380 390 400 410 420
MVSADRLLDE QNKQPYYALR AQVDAAAMGK LKGLQIRPGM AVQVFVRTGE RSLLNYLFKP
430
LFDRAHVALA EN