Q02981

SS
Gene name
YPL109C (LPH17C)
Protein name
ABC1 family protein YPL109C, mitochondrial
Names
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YPL109C
EC number
Protein Class

Descriptions

YPL109C is a UbiB family mitochondrial protein. This protein may have an autoinhibitory region, specifically containing KxGQ motif, which occludes the binding site of the catalytic domain within the same polypeptide. The KxGQ motif in YPL109C may be also involved in autoinhibition.

Autoinhibitory domains (AIDs)

178-181 (KxGQ motif) SS

Target domain

200-538 (ADCK2-like domain)

Relief mechanism

PTM

Assay

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q02981

Entry ID Method Resolution Chain Position Source
AF-Q02981-F1 Predicted AlphaFoldDB

10 variants for Q02981

Variant ID(s) Position Change Description Diseaes Association Provenance
s16-347301 30 F>L No SGRP
s16-347207 61 P>R No SGRP
s16-347161 76 N>K No SGRP
s16-347118 91 T>A No SGRP
s16-347042 116 V>A No SGRP
s16-346995 132 L>V No SGRP
s16-346609 260 D>E No SGRP
s16-346569 274 I>F No SGRP
s16-346505 295 C>F No SGRP
s16-345836 518 P>L No SGRP

No associated diseases with Q02981

1 regional properties for Q02981

Type Name Position InterPro Accession
domain ADCK2-like dom 200 - 538 IPR044095

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q7Z695 ADCK2 Uncharacterized aarF domain-containing protein kinase 2 Homo sapiens (Human) SS
10 20 30 40 50 60
MSFLKFAYRN SWRYYSKSTR HFHKIPIRQF IIPTSIAFYL TQNSFPKQNC LIYNDSLKPD
70 80 90 100 110 120
PKGDTFEMGL YVSSENELQE KLKSFRSAKI TESRNKLIRY LRIFWFGFND NIVEPVCTIL
130 140 150 160 170 180
RFLEISAIFL PLLLLYPISW FGHKLKITDT NITETRGSLI WCQLLRKALE LAGPSFIKLG
190 200 210 220 230 240
QWAGSRTDIF SHALCHELGK LHSNVTAHSL SFTLEKLSQA LKVDKIEDAF DEFNRTPIGV
250 260 270 280 290 300
GSIAQVYVGE LSQKYIDKYD NIQIGKDGNR WCAIKILHPN VRSQIRRDLK IMKFCADAIN
310 320 330 340 350 360
WIPTMEWLSL PSEVDQFSIL MNIQLDLRIE ALNLERFNEN FKNSIQVKFP KPFLPLSNRD
370 380 390 400 410 420
VMFEEHVYGL SMEKFLSTKK QINDVELCKK VSDPFVDAFL QMLILDDFVH ADLHPGNVII
430 440 450 460 470 480
RFVKTNKYGT NIISSELESY RITHDLRKKI EEDQDQDFVG KLKSVLTNYT PQICFIDTGI
490 500 510 520 530 540
ITELNEKNRI NFIALFNALA RFDGYRAGEL MIERSRTPET AIDKEVFAFK VEKLVDKVKQ
550 560 570 580 590 600
RTFTLGTVSI GDLLDQMLSM VRSHHVRMES DFVSVVVAIL LLEGIGRQLD PNLDLFESSL
610 620 630 640 650
PILREFGFKR EAKSLLKDAS TLSMLKIWVG LEVRQLMHLS MKQIYDLVRT DQLCPNY