Q02382

PR
Gene name
ORF3
Protein name
Probable RNA-directed RNA polymerase
Names
Species
Leishmania RNA virus 1 - 1 (isolate Leishmania guyanensis) (LRV-1-1)
KEGG Pathway
vg:1446405
EC number
2.7.7.48: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

116-187 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q02382

Entry ID Method Resolution Chain Position Source

No variants for Q02382

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q02382

No associated diseases with Q02382

No regional properties for Q02382

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q02382

Functions

Description
EC Number 2.7.7.48 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQCPNQNHML VNRAMVVAAL DSFEDARRII SGVLDLSRLT NTSVKGQHTN DTNYFSRYSN
70 80 90 100 110 120
FFSQMPAIIL NQLKCCIKAQ VDDAVKMVLQ KAKKVEVSKP VEKMLTFTTL NTYLGYPEST
130 140 150 160 170 180
GCVMEYTEEQ SGPIAAKLLI TLLSSTLNAM VRPKSDPNIS QNKIPRHYYQ LKVHVGAQKK
190 200 210 220 230 240
VNLTAIEVIR GCQHECSVVY CEFVRYSAYF AGLYDDQVAA ILLYAVAAHN VQGFGARFCV
250 260 270 280 290 300
LWALMCVRIA GFADDINIYI KHRGMSGLLP QLVEMKCLLG RGVNEIDVET EARRRLDVGS
310 320 330 340 350 360
LSMQRLDENE LRAAVRLIYS EELRRPVTYP LICDFWSSRW LWAANGSHSR ALEHAHPELA
370 380 390 400 410 420
TRKEGQAYRK AVMEQWQHNP MDRWDGTVYV TPSAKLEHGK TRLLLACDTL SYMWFEYALR
430 440 450 460 470 480
PVERIWENSN VILDPGSMGN CGIATRINGW RNGMPGQSFF AVDYDDFNSQ HTLMSQKIVF
490 500 510 520 530 540
EELFHHIGYN ASWVKTLVDS FDSMELWIKG KCAGIMAGTL MSGHRATSFI NSVLNRAYII
550 560 570 580 590 600
CAGGHVPTSM HVGDDILMSC TLGHADNLIA NLNRKGVRLN ASKQVFSKTS GEFLRVAHRE
610 620 630 640 650 660
HTSHGYLARV ISSAVSGNWV SDHTLNQQEA LMNAIVCCRG ILNRSLPGEK NPVVRVISRS
670 680 690 700 710 720
VSKRTKIEEK TIRLLLSGRA CLKGGVVYGE QTNYIQVYRI NCRVERSEEK LPPYRHATED
730 740 750 760 770 780
YLNNHLADIE VMAVRQYGSD IADIMAQASW KKSMSTEGAE DVSRLSLQRD KTLPCLHCIT
790 800 810 820 830 840
EKETSLLPVR YGLFSSYPIL MMLKDRIPIK EALKLAVTIG YRPQPNSDLE LDLWGESNNS
850 860 870
CAIEGVLPYN EATSLAQKLP CGGVVIQVIH NVYV