Q02129

PR
Gene name
hisG (LL1208, L0066)
Protein name
ATP phosphoribosyltransferase
Names
ATP-PRT, ATP-PRTase
Species
Lactococcus lactis subsp lactis (strain IL1403) (Streptococcus lactis)
KEGG Pathway
lla:L0066
EC number
2.4.2.17: Pentosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

80-153 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for Q02129

Entry ID Method Resolution Chain Position Source
1Z7M X-ray 290 A E/F/G/H 1-208 PDB
1Z7N X-ray 325 A E/F/G/H 1-208 PDB
AF-Q02129-F1 Predicted AlphaFoldDB

No variants for Q02129

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q02129

No associated diseases with Q02129

2 regional properties for Q02129

Type Name Position InterPro Accession
domain ATP phosphoribosyltransferase, catalytic domain 2 - 203 IPR013820
conserved_site ATP phosphoribosyltransferase, conserved site 142 - 163 IPR018198

Functions

Description
EC Number 2.4.2.17 Pentosyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP phosphoribosyltransferase activity Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate.

1 GO annotations of biological process

Name Definition
histidine biosynthetic process The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIKIAITKGR IQKQVTKLLE NADYDVEPIL NLGRELQIKT KDDLQIIFGK PNDVITFLEH
70 80 90 100 110 120
GIVDIGFVGK DTLDENDFDD YYELLYLKIG QCIFALASYP DFSNKNFQRH KRIASKYPRV
130 140 150 160 170 180
TKKYFAQKQE DIEIIKLEGS VELGPVVGLA DAIVDIVETG NTLSANGLEV IEKISDISTR
190 200
MIVNKSSFKF KKDKIIEMVE RLEDAQTN