Q01X96

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Solibacter usitatus (strain Ellin6076)
KEGG Pathway
sus:Acid_4760
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

777-858 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q01X96

Entry ID Method Resolution Chain Position Source
AF-Q01X96-F1 Predicted AlphaFoldDB

No variants for Q01X96

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q01X96

No associated diseases with Q01X96

5 regional properties for Q01X96

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 617 - 804 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 6 - 117 IPR007695
domain DNA mismatch repair protein MutS, core 270 - 597 IPR007696
domain DNA mismatch repair protein MutS, connector domain 126 - 252 IPR007860
domain DNA mismatch repair protein MutS, clamp 434 - 524 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDASTPLMR QYNSIKEQVP NALLMFRLGD FYELFFEDAV TAARELEITL TARNKEKGNA
70 80 90 100 110 120
IPMCGVPYHA AEGYISRLIQ KGFRVAICDQ VEDAKLAKKL VRREITRVVT PGTAMDSNLV
130 140 150 160 170 180
RSRENNFLAA VGRSGSRSAV AHVDVSTGEF RVTEMEPEEV AGALEHLGAR EVLFPGDLPL
190 200 210 220 230 240
LTGEDRSGLR FVRTELEDWV FTHDYSDRTL RDHFKLLSLD GCGLANRAAA IGAAGAILHY
250 260 270 280 290 300
LRDTQRAALD HLDRPTYYDR ADSMVLDSVT VRNLELIEPL FAADAGGIHA QPTVLGVLDQ
310 320 330 340 350 360
TLTGMGGRLL RQRLLRPSMN RAEIEQRLDA VGELQQQTIL RAELRKQLSG ILDLERLLAK
370 380 390 400 410 420
VTLGSAGPRD VLALGRSLEK IPALKRCFDT QQAARLRNLH DRLDELADVA SLILDCISDE
430 440 450 460 470 480
PPLNLVDGGT IRAGFHPELD ELRDLSQNGK QYIAQIEARE RQRTGIGSLK VRFNNVFGYY
490 500 510 520 530 540
IEITRANQHL APADYERKQT LANAERFTTP ELKDYERKVL DAEDKILTLE KELFSDVRKR
550 560 570 580 590 600
AAAHAQRIRA AAAAVAELDV TASLAQVAAE NRYQRPCFSD SGEMRIMAGR HPVIERLTEQ
610 620 630 640 650 660
EAGRFIPNDL YLNDSTDLLA IITGPNMGGK STYLRQAALI AILAQIGSFV PAESASLPVI
670 680 690 700 710 720
DRIFTRIGAS DNLARGRSTF MVEMTETAVI LNTATPRSFI VLDEVGRGTA TYDGLALAWA
730 740 750 760 770 780
VVEYIHQRTR AKTLFATHYH ELTELAEQLS GVRNLMVSVK EAGDHIIFLR KVEPGKADRS
790 800 810 820 830 840
YGIEVARLAG LPISVIERAR DVLKLHERTE HAVSGELVKS EDHGPVQIQM FEPVGYGIAE
850 860
RIRAINVDEL RPIEALQLLS ELQKELKRS