Q01VB2

PR
Gene name
rpoC
Protein name
DNA-directed RNA polymerase subunit beta'
Names
RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'
Species
Solibacter usitatus (strain Ellin6076)
KEGG Pathway
sus:Acid_5456
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1348-1403 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q01VB2

Entry ID Method Resolution Chain Position Source
AF-Q01VB2-F1 Predicted AlphaFoldDB

No variants for Q01VB2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q01VB2

No associated diseases with Q01VB2

7 regional properties for Q01VB2

Type Name Position InterPro Accession
domain RNA polymerase, alpha subunit 343 - 384 IPR000722-1
domain RNA polymerase, alpha subunit 389 - 484 IPR000722-2
domain RNA polymerase, N-terminal 234 - 513 IPR006592
domain RNA polymerase Rpb1, domain 3 488 - 652 IPR007066
domain RNA polymerase Rpb1, domain 1 14 - 341 IPR007080
domain RNA polymerase Rpb1, domain 5 766 - 1305 IPR007081
domain RNA polymerase Rpb1, domain 4 681 - 763 IPR007083

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

4 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
magnesium ion binding Binding to a magnesium (Mg) ion.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRSSPYDRAN LIADFDSIRI SLASPEKIRS WSHGEVTKPE TINYRTFKPE RDGLFCARIF
70 80 90 100 110 120
GPTQDWECLC GKYKRMKHRG VICDKCGVEV TLARVRRERL GHIELASPCS HVWFFKGLPS
130 140 150 160 170 180
RIGHLLDITL RELERVLYFE AYVIVDPGDG TGLSSGEVIT DERKRQLDQE FPGKFIAMMG
190 200 210 220 230 240
AEGIKELLKK IDVESLSEEI REKMKTEQSQ QKKLKHAKRL RVVESFRKSG NKPEWMILDV
250 260 270 280 290 300
IPVIPPELRP LVPLDGGRFA TSDLNDLYRR VINRNNRLKK LIELHAPDVI VRNEKRMLQE
310 320 330 340 350 360
AVDALFDNGR RGRVLRGANN RPLKSLSDTL KGKQGRFRQN LLGKRVDYSG RSVIVVGPDL
370 380 390 400 410 420
KLHQCGLPKK MALELFKPFI YHRLEQRGHC TTIKQAKELV EQQDPVVWDI LEEVIKDHPI
430 440 450 460 470 480
MLNRAPTLHR LGIQAFEPVL VEGKAIKIHP LVCTAFNADF DGDQMAVHIP LSPEAQIEAS
490 500 510 520 530 540
TLMLSANNIL SPAHGGPITI PTQDMVLGCY YLTKSRPGAK GEGRTFASTD DVLIALEMGE
550 560 570 580 590 600
VETLTPIKLR YTGKVIDLVH AFDTQNILHT EPIEFIKQYM DTTVGRVILN DNLPQDMPYI
610 620 630 640 650 660
NGLLKKKGLA QLVQYCYLKF GLHVTVHMLD EIKSLGFLYA TRAGISIGID DMVVPSEKAG
670 680 690 700 710 720
LVRDAEKEVV LVENQYQDGA ITHGERYNKI IEIWSKVTER VSDEMFTAME EDDRTGRYLN
730 740 750 760 770 780
PIYIMADSGA RGSKQQIRQL SGMRGLMAKP SGEIIETPIT ANFREGLNVL QYFISTHGAR
790 800 810 820 830 840
KGLADTALKT ADSGYLTRRL VDVAQDVIIS ENDCGTTEGI YVEPIIESGE IIEALRDRIV
850 860 870 880 890 900
GRVALEDQKD YEGNVIVGVN QEITEDLAAA IQAAGIERVK IRSVLTCESK RGVCVACYGR
910 920 930 940 950 960
NLATGRLVER GEAVGVIAAQ SIGEPGTQLT MRTFHIGGTA TRINEQSKQD AKSDGFARYI
970 980 990 1000 1010 1020
GIQTVRSKVG ELIAMNRNGI MAVVDDKGRE KERYPAVYGA RVLVEDGAPV KSNQVLLEWD
1030 1040 1050 1060 1070 1080
PYTFSILTEV SGVVHFKDLI DGLTMQERLD EVTGMSQLVV IDSPDEKRQP MIQVRPEGAT
1090 1100 1110 1120 1130 1140
GRGSEAKKYL MPTHAHLMVR DGEELHAGDV LAKIPRETTK TKDITGGLPR VVELFEARKP
1150 1160 1170 1180 1190 1200
RETAIIAEIN GTVKYGEVTK GQRKIYVEGE DGEKREYALP RGVHINVQEG EKVKAGEPLM
1210 1220 1230 1240 1250 1260
DGPRDPHDIL AVLGEKELQK YLVNEIQEVY RLQGVNINDK HLETISRQMM RWVKVEDIGD
1270 1280 1290 1300 1310 1320
TEFLPEEIVD KFKFRTENNK VLEAGGRPAQ GKAMLLGITK ASLSTDSFIS AASFQETTRV
1330 1340 1350 1360 1370 1380
LTEAAINGKV DYLRGLKENV IMGRLVPAGT GMEYYRQVKI AGEDVVEEPV AEPLDIIPGY
1390 1400
DEETRLQYAG GLPEDTGEES LAE