Q01961

PR
Gene name
PEX12 (PAS10)
Protein name
Peroxisome assembly protein 12
Names
Peroxin-12, Peroxisome assembly protein PAS10
Species
Komagataella pastoris (Yeast) (Pichia pastoris)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-44 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q01961

Entry ID Method Resolution Chain Position Source
AF-Q01961-F1 Predicted AlphaFoldDB

No variants for Q01961

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q01961

No associated diseases with Q01961

2 regional properties for Q01961

Type Name Position InterPro Accession
domain Zinc finger, RING-type 339 - 383 IPR001841
domain Pex, N-terminal 25 - 291 IPR006845

Functions

Description
EC Number
Subcellular Localization
  • Peroxisome membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of peroxisomal membrane The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
protein C-terminus binding Binding to a protein C-terminus, the end of a peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
protein import into peroxisome matrix The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDFYSNLDSR SLDSETPTLF EIISAQELEK LLTPSIRYIL VHYTQRYPRY LLKVANHFDE
70 80 90 100 110 120
LNLAIRGFIE FRQLSHWNST FIDKFYGLKK VRNHQTISTE RLQSQVPTLL EQRRRLSKTQ
130 140 150 160 170 180
IAVSLFEIVG VPYLRDKLDH LYDKLYPKLM MNNLDPKESL KTFVQYYFLK LYPILLSVLT
190 200 210 220 230 240
TIQVLLQVLY LSGTFKSPSI IMWLFKMKYA RLNSYDYTLD EQRVNKFLNK TSPGKLGTGN
250 260 270 280 290 300
NRIRPITLTE SLYLLYSDLT RPLKKGLLIT GGTLFPASIF LLKFLEWWNS SDFATKMNKP
310 320 330 340 350 360
RNPFSDSELP PPINLSKDLL ADRKIKKLLK KSQSNDGTCP LCHKQITNPA VIETGYVFCY
370 380 390 400
TCIFKHLTSS ELDEETGGRC PITGRRLLGC RINKTTGEWT VDGIRRLMM