Q01577

PR
Gene name
pkpA
Protein name
Serine/threonine-protein kinase pkpA
Names
Species
Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC 33097 / NRRL 1555)
KEGG Pathway
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

270-517 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

158-178 (Activation loop from InterPro)

Target domain

17-269 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for Q01577

Entry ID Method Resolution Chain Position Source
AF-Q01577-F1 Predicted AlphaFoldDB

No variants for Q01577

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q01577

No associated diseases with Q01577

2 regional properties for Q01577

Type Name Position InterPro Accession
domain Protein kinase domain 17 - 269 IPR000719
active_site Serine/threonine-protein kinase, active site 136 - 148 IPR008271

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

1 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPDYEKVIEA SGNGRYSKLN TVLGKGAYKV VYKAIDREEA INDNEITNVK VTRQEFKDLG
70 80 90 100 110 120
HEIDILKSVR HPNIITFHDA WYNETEFVFI TELMTSGTLR EYIRKLTPLP NIKIVKRWCR
130 140 150 160 170 180
QILKGLAYLH GHEPPIIHRD IKCDNIFING AHGEIKIGDM GTAEMKNGKK YTVIGTPEFM
190 200 210 220 230 240
APEMYEEQGY NEKVDIYAFG MCLLEMATGE YPYGECTNAV QVFKKVTQTI KPECLSRVQD
250 260 270 280 290 300
PELLTLVNIC LTPEDERMTA QEILEHRFLA VEPEVVLVSK DMTMKLLTLQ VVFKGMDKLS
310 320 330 340 350 360
VKFEFNADTD TAADVVAEMI EEQVLQNCYQ QLITCEINRI LRDIARNQGP PDKGEDEKIV
370 380 390 400 410 420
WRRENDIRSE LERAKKDLAL AVERVFEAEK KCELLEQHNI IAEERCKETI FALEQAKFQI
430 440 450 460 470 480
PDLLQPQPQP QPQPQPQPQP QPQFQLQPQL QYLSPQSTTS PGPTSDDNST NSTMLSSLES
490 500 510 520 530 540
ELSKLCVSGD EQVETTTHSA LMENVLAGKA KYYEYSNDTS IDKFVMDTAG ATNRSKDKQK
550 560 570 580 590 600
QWAAKLQDQD IMTVGDLRDL HDEDWSGIGL TVFALRALKN MLAGKKAAVT QRGLQGTRSG
610
ASTPVEEQEQ ELM