Q00873

PR
Gene name
CYT2
Protein name
Holocytochrome-c1 synthase
Names
Cytochrome c1 heme lyase, CC1HL
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YKL087C
EC number
4.4.1.17: Carbon-sulfur lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-103 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q00873

Entry ID Method Resolution Chain Position Source
AF-Q00873-F1 Predicted AlphaFoldDB

4 variants for Q00873

Variant ID(s) Position Change Description Diseaes Association Provenance
s11-277405 35 P>S No SGRP
s11-277398 37 N>S No SGRP
s11-277348 54 Y>H No SGRP
s11-277338 57 T>K No SGRP

No associated diseases with Q00873

1 regional properties for Q00873

Type Name Position InterPro Accession
conserved_site Cytochrome P450, conserved site 447 - 456 IPR017972

Functions

Description
EC Number 4.4.1.17 Carbon-sulfur lyases
Subcellular Localization
  • Mitochondrion inner membrane
  • Partially exposed to the intermembrane space
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrial intermembrane space The region between the inner and outer lipid bilayers of the mitochondrial envelope.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

2 GO annotations of molecular function

Name Definition
holocytochrome-c synthase activity Catalysis of the reaction: holocytochrome c = apocytochrome c + heme.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
cytochrome c-heme linkage The linkage of cytochromes and other heme proteins to heme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMSSDQQGKC PVDEETKKLW LREHGNEAHP GATAPGNQLE CSANPQDNDK TPEYHTTVDL
70 80 90 100 110 120
SQSREVSTIP RTNSDRNWIY PSEKQFYEAM MKKNWDPNSD DMKVVVPLHN SINERVWNYI
130 140 150 160 170 180
KSWEDKQGGE ACGGIKLTNF KGDSKKLTPR AWFRSRILHL AKPFDRHDWQ IDRCGKTVDY
190 200 210 220
VIDFYSTDLN DANSQQQPLI YLDVRPKLNS FEGFRLRFWK SLGF