Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q00673

Entry ID Method Resolution Chain Position Source
AF-Q00673-F1 Predicted AlphaFoldDB

No variants for Q00673

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q00673

No associated diseases with Q00673

2 regional properties for Q00673

Type Name Position InterPro Accession
domain NADH:ubiquinone oxidoreductase, 30kDa subunit 93 - 214 IPR001268
conserved_site NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site 174 - 195 IPR020396

Functions

Description
EC Number 7.1.1.2 Hydron translocation or charge separation linked to oxidoreductase reactions
Subcellular Localization
  • Mitochondrion inner membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
respirasome The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.

1 GO annotations of molecular function

Name Definition
NADH dehydrogenase (ubiquinone) activity Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MISRTLLKRT VPASRLLRSF TTSNVRLSAH EEDLVNVNNL PRPKPTENYV PLINPTEKYK
70 80 90 100 110 120
VQIEELHKFG TYIMSCLPKY IQQFSVWKDE LTIYVAPSAI RPVMSYLKNH TSCQFKAVMD
130 140 150 160 170 180
ITAADYPSRT NRFDVVYNLL SDRHNSRIRV KTYANETSPV PSVTPLFNGA NWYERETYDL
190 200 210 220 230 240
FGVFFVGHPD LRRIMTDYGF EGHPLRKDFP TTGYTEVRYD EEKKRVIYEP LELTQAWRNF
250 260 270
TVGSSVWEPV GEGKDFTPES FKLPTPQPEP EQEEKK