P9WQ17

PR
Gene name
glgE (Rv1327c, MTCY130.12c)
Protein name
Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase
Names
GMPMT, (1->4)-alpha-D-glucan:maltose-1-phosphate alpha-D-maltosyltransferase, (1->4)-alpha-D-glucan:phosphate alpha-D-maltosyltransferase
Species
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
KEGG Pathway
mtu:Rv1327c
EC number
2.4.99.16: Transferring other glycosyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

50-126 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P9WQ17

Entry ID Method Resolution Chain Position Source
AF-P9WQ17-F1 Predicted AlphaFoldDB

No variants for P9WQ17

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P9WQ17

No associated diseases with P9WQ17

2 regional properties for P9WQ17

Type Name Position InterPro Accession
domain Glycosyl hydrolase, family 13, catalytic domain 232 - 573 IPR006047
domain Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S 16 - 226 IPR021828

Functions

Description
EC Number 2.4.99.16 Transferring other glycosyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
hexosyltransferase activity Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor).
hydrolase activity, hydrolyzing O-glycosyl compounds Catalysis of the hydrolysis of any O-glycosyl bond.

3 GO annotations of biological process

Name Definition
alpha-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.
glycogen biosynthetic process The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
trehalose catabolic process The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSGRAIGTET EWWVPGRVEI DDVAPVVSCG VYPAKAVVGE VVPVSAAVWR EGHEAVAATL
70 80 90 100 110 120
VVRYLGVRYP HLTDRPRARV LPTPSEPQQR VKPLLIPMTS GQEPFVFHGQ FTPDRVGLWT
130 140 150 160 170 180
FRVDGWGDPI HTWRHGLIAK LDAGQGETEL SNDLLVGAVL LERAATGVPR GLRDPLLAAA
190 200 210 220 230 240
AALRTPGDPV TRTALALTPE IEELLADYPL RDLVTRGEQF GVWVDRPLAR FGAWYEMFPR
250 260 270 280 290 300
STGGWDDDGN PVHGTFATAA AELPRIAGMG FDVVYLPPIH PIGKVHRKGR NNSPTAAPTD
310 320 330 340 350 360
VGSPWAIGSD EGGHDTVHPS LGTIDDFDDF VSAARDLGME VALDLALQCA PDHPWAREHR
370 380 390 400 410 420
QWFTELPDGT IAYAENPPKK YQDIYPLNFD NDPEGLYDEV LRVVQHWVNH GVKFFRVDNP
430 440 450 460 470 480
HTKPPNFWAW LIAQVKTVDP DVLFLSEAFT PPARQYGLAK LGFTQSYSYF TWRTTKWELT
490 500 510 520 530 540
EFGNQIAELA DYRRPNLFVN TPDILHAVLQ HNGPGMFAIR AVLAATMSPA WGMYCGYELF
550 560 570 580 590 600
EHRAVREGSE EYLDSEKYEL RPRDFASALD QGRSLQPFIT RLNIIRRLHP AFQQLRTIHF
610 620 630 640 650 660
HHVDNDALLA YSKFDPATGD CVLVVVTLNA FGPEEATLWL DMAALGMEDY DRFWVRDEIT
670 680 690 700
GEEYQWGQAN YIRIDPARAV AHIINMPAVP YESRNTLLRR R