P9WNM1

PR
Gene name
tsf (Rv2889c, MTCY274.20c)
Protein name
Elongation factor Ts
Names
EF-Ts
Species
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
KEGG Pathway
mtu:Rv2889c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

3-140 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for P9WNM1

Entry ID Method Resolution Chain Position Source
7VMX X-ray 280 A A 1-271 PDB
AF-P9WNM1-F1 Predicted AlphaFoldDB

No variants for P9WNM1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P9WNM1

No associated diseases with P9WNM1

3 regional properties for P9WNM1

Type Name Position InterPro Accession
domain Translation elongation factor EFTs/EF1B, dimerisation 67 - 270 IPR014039
conserved_site Translation elongation factor Ts, conserved site 12 - 27 IPR018101-1
conserved_site Translation elongation factor Ts, conserved site 71 - 81 IPR018101-2

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
peptidoglycan-based cell wall A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome.

1 GO annotations of biological process

Name Definition
translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MANFTAADVK RLRELTGAGM LACKNALAET DGDFDKAVEA LRIKGAKDVG KRAERATAEG
70 80 90 100 110 120
LVAAKDGALI ELNCETDFVA KNAEFQTLAD QVVAAAAAAK PADVDALKGA SIGDKTVEQA
130 140 150 160 170 180
IAELSAKIGE KLELRRVAIF DGTVEAYLHR RSADLPPAVG VLVEYRGDDA AAAHAVALQI
190 200 210 220 230 240
AALRARYLSR DDVPEDIVAS ERRIAEETAR AEGKPEQALP KIVEGRLNGF FKDAVLLEQA
250 260 270
SVSDNKKTVK ALLDVAGVTV TRFVRFEVGQ A