P9WN96
Gene name |
ftsW (MT2213) |
Protein name |
Probable peptidoglycan glycosyltransferase FtsW |
Names |
PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase |
Species |
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) |
KEGG Pathway |
mtc:MT2213 |
EC number |
2.4.1.129: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P9WN96
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P9WN96-F1 | Predicted | AlphaFoldDB |
No variants for P9WN96
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P9WN96 | |||||
No associated diseases with P9WN96
1 regional properties for P9WN96
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Cell cycle, FtsW / RodA / SpoVE, conserved site | 370 - 394 | IPR018365 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.129 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| peptidoglycan glycosyltransferase activity | Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| cell wall organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. |
| peptidoglycan biosynthetic process | The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls. |
| regulation of cell shape | Any process that modulates the surface configuration of a cell. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLTRLLRRGT | SDTDGSQTRG | AEPVEGQRTG | PEEASNPGSA | RPRTRFGAWL | GRPMTSFHLI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IAVAALLTTL | GLIMVLSASA | VRSYDDDGSA | WVIFGKQVLW | TLVGLIGGYV | CLRMSVRFMR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RIAFSGFAIT | IVMLVLVLVP | GIGKEANGSR | GWFVVAGFSM | QPSELAKMAF | AIWGAHLLAA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RRMERASLRE | MLIPLVPAAV | VALALIVAQP | DLGQTVSMGI | ILLGLLWYAG | LPLRVFLSSL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AAVVVSAAIL | AVSAGYRSDR | VRSWLNPEND | PQDSGYQARQ | AKFALAQGGI | FGDGLGQGVA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KWNYLPNAHN | DFIFAIIGEE | LGLVGALGLL | GLFGLFAYTG | MRIASRSADP | FLRLLTATTT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LWVLGQAFIN | IGYVIGLLPV | TGLQLPLISA | GGTSTAATLS | LIGIIANAAR | HEPEAVAALR |
| 430 | 440 | 450 | 460 | 470 | 480 |
| AGRDDKVNRL | LRLPLPEPYL | PPRLEAFRDR | KRANPQPAQT | QPARKTPRTA | PGQPARQMGL |
| 490 | 500 | 510 | 520 | ||
| PPRPGSPRTA | DPPVRRSVHH | GAGQRYAGQR | RTRRVRALEG | QRYG |