P9WMV2

PR
Gene name
gmhB (MT0122.1)
Protein name
D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase
Names
D,D-heptose 1,7-bisphosphate phosphatase, HBP phosphatase
Species
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
KEGG Pathway
mtc:MT0122
EC number
3.1.3.83: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

118-188 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P9WMV2

Entry ID Method Resolution Chain Position Source
AF-P9WMV2-F1 Predicted AlphaFoldDB

No variants for P9WMV2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P9WMV2

No associated diseases with P9WMV2

2 regional properties for P9WMV2

Type Name Position InterPro Accession
domain Histidinol-phosphate phosphatase 10 - 153 IPR006543
domain HAD-superfamily hydrolase,subfamily IIIA 10 - 156 IPR006549

Functions

Description
EC Number 3.1.3.83 Phosphoric monoester hydrolases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
D,D-heptose 1,7-bisphosphate phosphatase activity Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate.
magnesium ion binding Binding to a magnesium (Mg) ion.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVAERAGHQW CLFLDRDGVI NRQVVGDYVR NWRQFEWLPG AARALKKLRA WAPYIVVVTN
70 80 90 100 110 120
QQGVGAGLMS AVDVMVIHRH LQMQLASDGV LIDGFQVCPH HRSQRCGCRK PRPGLVLDWL
130 140 150 160 170 180
GRHPDSEPLL SIVVGDSLSD LELAHNVAAA AGACASVQIG GASSGGVADA SFDSLWEFAV
AVGHARGERG