P9WMT1
Gene name |
obg |
Protein name |
GTPase Obg |
Names |
GTP-binding protein Obg |
Species |
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
KEGG Pathway |
mtu:Rv2440c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P9WMT1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P9WMT1-F1 | Predicted | AlphaFoldDB |
No variants for P9WMT1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P9WMT1 | |||||
No associated diseases with P9WMT1
5 regional properties for P9WMT1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GTP binding domain | 161 - 265 | IPR006073 |
| conserved_site | GTP1/OBG, conserved site | 212 - 225 | IPR006074 |
| domain | GTP1/OBG domain | 2 - 159 | IPR006169 |
| domain | GTP-binding protein OBG, C-terminal | 358 - 436 | IPR015349 |
| domain | OBG-type guanine nucleotide-binding (G) domain | 160 - 340 | IPR031167 |
Functions
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| ribosome | An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein autophosphorylation | The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation). |
| ribosome biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPRFVDRVVI | HTRAGSGGNG | CASVHREKFK | PLGGPDGGNG | GRGGSIVFVV | DPQVHTLLDF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HFRPHLTAAS | GKHGMGNNRD | GAAGADLEVK | VPEGTVVLDE | NGRLLADLVG | AGTRFEAAAG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GRGGLGNAAL | ASRVRKAPGF | ALLGEKGQSR | DLTLELKTVA | DVGLVGFPSA | GKSSLVSAIS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AAKPKIADYP | FTTLVPNLGV | VSAGEHAFTV | ADVPGLIPGA | SRGRGLGLDF | LRHIERCAVL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VHVVDCATAE | PGRDPISDID | ALETELACYT | PTLQGDAALG | DLAARPRAVV | LNKIDVPEAR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ELAEFVRDDI | AQRGWPVFCV | STATRENLQP | LIFGLSQMIS | DYNAARPVAV | PRRPVIRPIP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VDDSGFTVEP | DGHGGFVVSG | ARPERWIDQT | NFDNDEAVGY | LADRLARLGV | EEELLRLGAR |
| 430 | 440 | 450 | 460 | 470 | |
| SGCAVTIGEM | TFDWEPQTPA | GEPVAMSGRG | TDPRLDSNKR | VGAAERKAAR | SRRREHGDG |