P9WMD9

PR
Gene name
Rv0472c
Protein name
Uncharacterized HTH-type transcriptional regulator Rv0472c
Names
Species
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
KEGG Pathway
mtu:Rv0472c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-57 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P9WMD9

Entry ID Method Resolution Chain Position Source
AF-P9WMD9-F1 Predicted AlphaFoldDB

No variants for P9WMD9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P9WMD9

No associated diseases with P9WMD9

2 regional properties for P9WMD9

Type Name Position InterPro Accession
domain DNA-binding HTH domain, TetR-type 24 - 83 IPR001647
domain Tetracyclin repressor-like MT0489/Rv0472c, C-terminal domain 89 - 207 IPR045823

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

1 GO annotations of biological process

Name Definition
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAERIPAVTV KTDGRKRRWH QHKVERRNEL VDGTIEAIRR HGRFLSMDEI AAEIGVSKTV
70 80 90 100 110 120
LYRYFVDKND LTTAVMMRFT QTTLIPNMIA ALSADMDGFE LTREIIRVYV ETVAAQPEPY
130 140 150 160 170 180
RFVMANSSAS KSKVIADSER IIARMLAVML RRRMQEAGMD TGGVEPWAYL IVGGVQLATH
190 200 210 220 230
SWMSDPRMSS DELIDYLTML SWSALCGIVE AGGSLEKFRE QPHPSPIVPA WGQV