P9WKC8

PR
Gene name
tgs1 (MT3216)
Protein name
Probable diacyglycerol O-acyltransferase tgs1
Names
TGS1, Probable triacylglycerol synthase tgs1
Species
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
KEGG Pathway
mtc:MT3216
EC number
2.3.1.20: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

129-207 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P9WKC8

Entry ID Method Resolution Chain Position Source
AF-P9WKC8-F1 Predicted AlphaFoldDB

No variants for P9WKC8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P9WKC8

No associated diseases with P9WKC8

2 regional properties for P9WKC8

Type Name Position InterPro Accession
domain O-acyltransferase, WSD1-like, N-terminal 4 - 256 IPR004255
domain O-acyltransferase WSD1, C-terminal 299 - 442 IPR009721

Functions

Description
EC Number 2.3.1.20 Transferring groups other than amino-acyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
diacylglycerol O-acyltransferase activity Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.

2 GO annotations of biological process

Name Definition
glycerol metabolic process The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
triglyceride biosynthetic process The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNHLTTLDAG FLKAEDVDRH VSLAIGALAV IEGPAPDQEA FLSSLAQRLR PCTRFGQRLR
70 80 90 100 110 120
LRPFDLGAPK WVDDPDFDLG RHVWRIALPR PGNEDQLFEL IADLMARRLD RGRPLWEVWV
130 140 150 160 170 180
IEGLADSKWA ILTKLHHCMA DGIAATHLLA GLSDESMSDS FASNIHTTMQ SQSASVRRGG
190 200 210 220 230 240
FRVNPSEALT ASTAVMAGIV RAAKGASEIA AGVLSPAASS LNGPISDLRR YSAAKVPLAD
250 260 270 280 290 300
VEQVCRKFDV TINDVALAAI TESYRNVFIQ RGERPRFDSL RTLVPVSTRS NSALSKTDNR
310 320 330 340 350 360
VSLMLPNLPV DQENPLQRLR IVHSRLTRAK AGGQRQFGNT LMAIANRLPF PMTAWAVGLL
370 380 390 400 410 420
MRLPQRGVVT VATNVPGPRR PLQIMGRRVL DLYPVSPIAM QLRTSVAMLS YADDLYFGIL
430 440 450 460
ADYDVVADAG QLARGIEDAV ARLVAISKRR KVTRRRGALS LVV