P9WJV3

PR
Gene name
mmpL4 (Rv0450c, MTV037.14c)
Protein name
Siderophore exporter MmpL4
Names
Species
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
KEGG Pathway
mtu:Rv0450c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

22-165 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P9WJV3

Entry ID Method Resolution Chain Position Source
AF-P9WJV3-F1 Predicted AlphaFoldDB

No variants for P9WJV3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P9WJV3

No associated diseases with P9WJV3

2 regional properties for P9WJV3

Type Name Position InterPro Accession
domain Membrane transport protein MMPL domain 59 - 388 IPR004869-1
domain Membrane transport protein MMPL domain 613 - 943 IPR004869-2

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
peptidoglycan-based cell wall A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
biological process involved in interaction with host An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSTKFANDSN TNARPEKPFI ARMIHAFAVP IILGWLAVCV VVTVFVPSLE AVGQERSVSL
70 80 90 100 110 120
SPKDAPSFEA MGRIGMVFKE GDSDSFAMVI IEGNQPLGDA AHKYYDGLVA QLRADKKHVQ
130 140 150 160 170 180
SVQDLWGDPL TAAGVQSNDG KAAYVQLSLA GNQGTPLANE SVEAVRSIVE STPAPPGIKA
190 200 210 220 230 240
YVTGPSALAA DMHHSGDRSM ARITMVTVAV IFIMLLLVYR SIITVVLLLI TVGVELTAAR
250 260 270 280 290 300
GVVAVLGHSG AIGLTTFAVS LLTSLAIAAG TDYGIFIIGR YQEARQAGED KEAAYYTMYR
310 320 330 340 350 360
GTAHVILGSG LTIAGATFCL SFARMPYFQT LGIPCAVGML VAVAVALTLG PAVLHVGSRF
370 380 390 400 410 420
GLFDPKRLLK VRGWRRVGTV VVRWPLPVLV ATCAIALVGL LALPGYKTSY NDRDYLPDFI
430 440 450 460 470 480
PANQGYAAAD RHFSQARMKP EILMIESDHD MRNPADFLVL DKLAKGIFRV PGISRVQAIT
490 500 510 520 530 540
RPEGTTMDHT SIPFQISMQN AGQLQTIKYQ RDRANDMLKQ ADEMATTIAV LTRMHSLMAE
550 560 570 580 590 600
MASTTHRMVG DTEEMKEITE ELRDHVADFD DFWRPIRSYF YWEKHCYGIP ICWSFRSIFD
610 620 630 640 650 660
ALDGIDKLSE QIGVLLGDLR EMDRLMPQMV AQIPPQIEAM ENMRTMILTM HSTMTGIFDQ
670 680 690 700 710 720
MLEMSDNATA MGKAFDAAKN DDSFYLPPEV FKNKDFQRAM KSFLSSDGHA ARFIILHRGD
730 740 750 760 770 780
PQSPEGIKSI DAIRTAAEES LKGTPLEDAK IYLAGTAAVF HDISEGAQWD LLIAAISSLC
790 800 810 820 830 840
LIFIIMLIIT RAFIAAAVIV GTVALSLGAS FGLSVLLWQH ILAIHLHWLV LAMSVIVLLA
850 860 870 880 890 900
VGSDYNLLLV SRFKQEIGAG LKTGIIRSMG GTGKVVTNAG LVFAVTMASM AVSDLRVIGQ
910 920 930 940 950 960
VGTTIGLGLL FDTLIVRSFM TPSIAALLGR WFWWPLRVRS RPARTPTVPS ETQPAGRPLA
MSSDRLG