P9WHW4
Gene name |
pstP (mstp, ppp, MT0021) |
Protein name |
Serine/threonine protein phosphatase PstP |
Names |
Mycobacterial Ser/Thr phosphatase, Mstp, PP2C-family Ser/Thr phosphatase |
Species |
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) |
KEGG Pathway |
mtc:MT0021 |
EC number |
3.1.3.16: Phosphoric monoester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P9WHW4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P9WHW4-F1 | Predicted | AlphaFoldDB |
No variants for P9WHW4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P9WHW4 | |||||
No associated diseases with P9WHW4
1 regional properties for P9WHW4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | PPM-type phosphatase-like domain | 5 - 238 | IPR001932 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.3.16 | Phosphoric monoester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| myosin phosphatase activity | Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein dephosphorylation | The process of removing one or more phosphoric residues from a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARVTLVLRY | AARSDRGLVR | ANNEDSVYAG | ARLLALADGM | GGHAAGEVAS | QLVIAALAHL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DDDEPGGDLL | AKLDAAVRAG | NSAIAAQVEM | EPDLEGMGTT | LTAILFAGNR | LGLVHIGDSR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GYLLRDGELT | QITKDDTFVQ | TLVDEGRITP | EEAHSHPQRS | LIMRALTGHE | VEPTLTMREA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RAGDRYLLCS | DGLSDPVSDE | TILEALQIPE | VAESAHRLIE | LALRGGGPDN | VTVVVADVVD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YDYGQTQPIL | AGAVSGDDDQ | LTLPNTAAGR | ASAISQRKEI | VKRVPPQADT | FSRPRWSGRR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LAFVVALVTV | LMTAGLLIGR | AIIRSNYYVA | DYAGSVSIMR | GIQGSLLGMS | LHQPYLMGCL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SPRNELSQIS | YGQSGGPLDC | HLMKLEDLRP | PERAQVRAGL | PAGTLDDAIG | QLRELAANSL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LPPCPAPRAT | SPPGRPAPPT | TSETTEPNVT | SSPASPSPTT | SASAPTGTTP | AIPTSASPAA |
| 490 | 500 | 510 | |||
| PASPPTPWPV | TSSPTMAALP | PPPPQPGIDC | RAAA |