P9WH35

PR
Gene name
rpsD
Protein name
30S ribosomal protein S4
Names
Species
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
KEGG Pathway
mtu:Rv3458c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-76 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

11 structures for P9WH35

Entry ID Method Resolution Chain Position Source
5V93 EM 400 A d 1-201 PDB
7KGB EM 270 A d 1-201 PDB
7MSC EM 297 A d 1-201 PDB
7MSH EM 323 A d 1-201 PDB
7MSM EM 279 A d 1-201 PDB
7MSZ EM 310 A d 1-201 PDB
7MT2 EM 276 A d 1-201 PDB
7MT3 EM 280 A d 1-201 PDB
7MT7 EM 271 A d 1-201 PDB
7SFR EM 260 A d 1-201 PDB
AF-P9WH35-F1 Predicted AlphaFoldDB

No variants for P9WH35

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P9WH35

No associated diseases with P9WH35

3 regional properties for P9WH35

Type Name Position InterPro Accession
domain Ribosomal protein S4/S9, N-terminal 3 - 90 IPR001912
domain RNA-binding S4 domain 91 - 153 IPR002942
conserved_site Ribosomal protein S4, conserved site 89 - 113 IPR018079

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
peptidoglycan-based cell wall A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
small ribosomal subunit The smaller of the two subunits of a ribosome.

2 GO annotations of molecular function

Name Definition
rRNA binding Binding to a ribosomal RNA.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

2 GO annotations of biological process

Name Definition
positive regulation of translational fidelity Any process that increases the ability of the translational apparatus to interpret the genetic code.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARYTGPVTR KSRRLRTDLV GGDQAFEKRP YPPGQHGRAR IKESEYLLQL QEKQKARFTY
70 80 90 100 110 120
GVMEKQFRRY YEEAVRQPGK TGEELLKILE SRLDNVIYRA GLARTRRMAR QLVSHGHFNV
130 140 150 160 170 180
NGVHVNVPSY RVSQYDIVDV RDKSLNTVPF QIARETAGER PIPSWLQVVG ERQRVLIHQL
190 200
PERAQIDVPL TEQLIVEYYS K