P9WGM6

PR
Gene name
mtrA (MT3344)
Protein name
DNA-binding response regulator MtrA
Names
Species
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
KEGG Pathway
mtc:MT3344
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

92-164 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P9WGM6

Entry ID Method Resolution Chain Position Source
AF-P9WGM6-F1 Predicted AlphaFoldDB

No variants for P9WGM6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P9WGM6

No associated diseases with P9WGM6

3 regional properties for P9WGM6

Type Name Position InterPro Accession
domain Signal transduction response regulator, receiver domain 6 - 120 IPR001789
domain OmpR/PhoB-type DNA-binding domain 128 - 227 IPR001867
domain MtrA, receiver domain 6 - 111 IPR047673

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
phosphorelay signal transduction system A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDTMRQRILV VDDDASLAEM LTIVLRGEGF DTAVIGDGTQ ALTAVRELRP DLVLLDLMLP
70 80 90 100 110 120
GMNGIDVCRV LRADSGVPIV MLTAKTDTVD VVLGLESGAD DYIMKPFKPK ELVARVRARL
130 140 150 160 170 180
RRNDDEPAEM LSIADVEIDV PAHKVTRNGE QISLTPLEFD LLVALARKPR QVFTRDVLLE
190 200 210 220
QVWGYRHPAD TRLVNVHVQR LRAKVEKDPE NPTVVLTVRG VGYKAGPP