P9WGJ9
Gene name |
embR (Rv1267c, MTCY50.15) |
Protein name |
Transcriptional regulatory protein EmbR |
Names |
|
Species |
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
KEGG Pathway |
mtu:Rv1267c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for P9WGJ9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 2FEZ | X-ray | 200 A | A | 1-388 | PDB |
| 2FF4 | X-ray | 190 A | A/B | 1-388 | PDB |
| AF-P9WGJ9-F1 | Predicted | AlphaFoldDB |
No variants for P9WGJ9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P9WGJ9 | |||||
No associated diseases with P9WGJ9
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| peptidoglycan-based cell wall | A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| phosphorelay signal transduction system | A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGSATVEKR | LDFGLLGPLQ | MTIDGTPVPS | GTPKQRAVLA | MLVINRNRPV | GVDALITALW |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EEWPPSGARA | SIHSYVSNLR | KLLGGAGIDP | RVVLAAAPPG | YRLSIPDNTC | DLGRFVAEKT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AGVHAAAAGR | FEQASRHLSA | ALREWRGPVL | DDLRDFQFVE | PFATALVEDK | VLAHTAKAEA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EIACGRASAV | IAELEALTFE | HPYREPLWTQ | LITAYYLSDR | QSDALGAYRR | VKTTLADDLG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IDPGPTLRAL | NERILRQQPL | DAKKSAKTTA | AGTVTVLDQR | TMASGQQAVA | YLHDIASGRG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YPLQAAATRI | GRLHDNDIVL | DSANVSRHHA | VIVDTGTNYV | INDLRSSNGV | HVQHERIRSA |
| 370 | 380 | ||||
| VTLNDGDHIR | ICDHEFTFQI | SAGTHGGT |