P98118

PR
Gene name
PROS1 (PROS)
Protein name
Vitamin K-dependent protein S
Names
Species
Oryctolagus cuniculus (Rabbit)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-68 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P98118

Entry ID Method Resolution Chain Position Source
AF-P98118-F1 Predicted AlphaFoldDB

No variants for P98118

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P98118

No associated diseases with P98118

16 regional properties for P98118

Type Name Position InterPro Accession
ptm EGF-type aspartate/asparagine hydroxylation site 105 - 116 IPR000152-1
ptm EGF-type aspartate/asparagine hydroxylation site 188 - 199 IPR000152-2
ptm EGF-type aspartate/asparagine hydroxylation site 227 - 238 IPR000152-3
domain Gamma-carboxyglutamic acid-rich (GLA) domain 2 - 58 IPR000294
domain EGF-like domain 88 - 126 IPR000742-1
domain EGF-like domain 131 - 171 IPR000742-2
domain EGF-like domain 172 - 213 IPR000742-3
domain EGF-like domain 217 - 254 IPR000742-4
domain Laminin G domain 270 - 446 IPR001791-1
domain Laminin G domain 455 - 636 IPR001791-2
domain EGF-like calcium-binding domain 80 - 126 IPR001881-1
domain EGF-like calcium-binding domain 128 - 171 IPR001881-2
domain EGF-like calcium-binding domain 172 - 213 IPR001881-3
domain EGF-like calcium-binding domain 214 - 254 IPR001881-4
conserved_site EGF-like calcium-binding, conserved site 172 - 197 IPR018097-1
conserved_site EGF-like calcium-binding, conserved site 214 - 236 IPR018097-2

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

1 GO annotations of molecular function

Name Definition
calcium ion binding Binding to a calcium ion (Ca2+).

2 GO annotations of biological process

Name Definition
blood coagulation The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
fibrinolysis A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
GHASQVLVRK RRANSMLEET KKGNLERECI EELCNKEEAR EVFENDPETD YFYPKYLGCL
70 80 90 100 110 120
GSFRAKLFTA TRRSANGYPD LRSCVNAIPD QCNPLPCSEE GYLNCKDGQA TFTCICKPGW
130 140 150 160 170 180
QGEKCEIDIN ECKDPTNING GCSQICDNTA GSYHCSCKSG FVMLANEKDC KDMDECSVKP
190 200 210 220 230 240
SVCGTAVCKN TPGDFECECS EGYRYNPTAK SCEDIDECSE NMCAQLCVNY PGGYSCYCDG
250 260 270 280 290 300
KKGFKLAQDK KSCEAVPVCL PLDLDKNYQL LYLAEQFVGA VLYLKFHLPE ITRFSAEFDF
310 320 330 340 350 360
RTYDSEGVIL YAESLDHSTW FLIALRQGKI EIQFKNDYAA QITTGGQVIN DGLWNMVSVE
370 380 390 400 410 420
ELEHSVSIKI AQEPVMNINK PGSLFKPTNG FLETKVYFAG LPRKVENALI RPINPRLDGC
430 440 450 460 470 480
MRGWNLMKQG ASGVKEIIQQ KQKKHCLVTV EKGSYYPGSG IAQFHIDYNN LSYVEDWQVN
490 500 510 520 530 540
VTLNIRPSTG TGVMLTLVSG NTLPFALSLV QSTSETSQDI LVSVENRVIY QLESISLCSG
550 560 570 580 590 600
QQSQLEFSVS RNHLELSTPL VKDVIYSEDL QRHLAVLDEA MKGTVTTYLG GLPEVPFNAT
610 620 630 640
PVNAFYNGCM EVNINGVQLD LDEAISKHND IRAHSCPSVW NDKTNS