Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P97280
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P97280-F1 | Predicted | AlphaFoldDB |
No variants for P97280
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P97280 | |||||
No associated diseases with P97280
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| serine-type endopeptidase inhibitor activity | Binds to and stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| hyaluronan metabolic process | The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MWWPYLVLAL | LSGLEASGFP | RSPLRLLGKR | SLPEGVVDGV | EVYSTKISCK | VTSRFAHNVV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TTRAVNRADQ | AKEVSFDVEL | PKTAFITNFT | LTIDGVTYPG | NIKEKEVAQK | QYDKAVSQGK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TAGLVKASGR | KLEKFTVSVN | VAAGSKVTFE | LTYEELLKRH | KGKYEMYLKV | QPKQLVRHFE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IDAHIFEPQG | ISMLDAEASF | ITNDLLGSAL | TKSFSGKKGH | VSFKPSLDQQ | RSCPTCTDSL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LNGDFTIVYD | VNRESPGNVQ | VVNGYFVHFF | APQGLPVVPK | NIVFVIDISG | SMAGRKIQQT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RVALLKILDD | MKQDDYLNFI | LFSTGVTTWK | DSLVQATPAN | LEEARTFVRS | ISDQGMTNIN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DGLLRGIRML | TDAREQHTVP | ERSTSIIIML | TDGDANTGES | RPEKIQENVR | KAIEGRFPLY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NLGFGNNLNY | NFLETMALEN | HGVARRIYED | SDANLQLQGF | YEEVANPLLT | NVEVEYPENA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ILDLTKNSYP | HFYDGSETAV | AGRLADSDMN | NFKADVKGHG | ALNDLTFTEE | VDMKEMDAAL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KEQGYIFGNY | IERLWAYLTI | EQLLEKRKNA | HGEEKENLTA | QALELSLKYH | FVTPLTPMVV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TKPEDNEDQT | SIADKPGEDA | PYAATSTAYL | TSHQSPPTPY | YYVDGDPHFI | IQVPGKNDTI |
| 670 | 680 | 690 | 700 | 710 | 720 |
| CFNIDEKPGT | VLRLIQDPVT | GITVTGQIIG | DKGSSPYSRT | GKTYFGKLGI | THAWMDFRIE |
| 730 | 740 | 750 | 760 | 770 | 780 |
| VTTEKIILGT | EDELSTFSWL | DTVTITQTGL | FVAINRKKNM | VVSFGDGVNF | VIVLHQVWKK |
| 790 | 800 | 810 | 820 | 830 | 840 |
| HPLHQDFLGF | YVVDSHRMSA | RTHGLLGQFF | RPFDFEVSDV | RPGSDPAKPD | ATMVVKNHQL |
| 850 | 860 | 870 | 880 | ||
| TVTRGSQRDY | RKDASVGTKV | TCWFVHNNGE | GLIDGVHTDY | IVPSLF |