P97275

PR
Gene name
AGPS
Protein name
Alkyldihydroxyacetonephosphate synthase, peroxisomal
Names
Alkyl-DHAP synthase, Alkylglycerone-phosphate synthase
Species
Cavia porcellus (Guinea pig)
KEGG Pathway
cpoc:100734021
EC number
2.5.1.26: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-187 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

10 structures for P97275

Entry ID Method Resolution Chain Position Source
4BBY X-ray 190 A A/B/C/D 1-658 PDB
4BC7 X-ray 240 A A/B/C/D 1-658 PDB
4BC9 X-ray 241 A A/B/C/D 1-658 PDB
4BCA X-ray 240 A A/B/C/D 1-658 PDB
5ADZ X-ray 220 A A/B/C/D 1-658 PDB
5AE1 X-ray 210 A A/B/C/D 1-658 PDB
5AE2 X-ray 200 A A/B/C/D 1-658 PDB
5AE3 X-ray 218 A A/B/C/D 1-658 PDB
6GOU X-ray 290 A A/B/C/D 1-658 PDB
AF-P97275-F1 Predicted AlphaFoldDB

No variants for P97275

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P97275

No associated diseases with P97275

No regional properties for P97275

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P97275

Functions

Description
EC Number 2.5.1.26 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Peroxisome membrane
  • Peroxisome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
peroxisomal membrane The lipid bilayer surrounding a peroxisome.
peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.

2 GO annotations of molecular function

Name Definition
alkylglycerone-phosphate synthase activity Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion.
FAD binding Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.

1 GO annotations of biological process

Name Definition
ether lipid biosynthetic process The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAEAAAAAAA AAAAGETSAS SGSAAERDPD QDRAGRRLRV LSGHLLGRPQ EALSTNECKA
70 80 90 100 110 120
RRAASAATAA PTATPAAPES GIIPKKRQEL MKWNGWGYND SKFFLNKKGQ LELTGKRYPL
130 140 150 160 170 180
SGVALPTFKD WIQNTFGINL DHKTTSKASL NPSDTPPSIV NEDFLHELKK TNISYSQEAD
190 200 210 220 230 240
DRVFRAHGHC LHEIFLLREG MFERIPDIVL WPTCHDDVVK IVNLACKYNL CIIPIGGGTS
250 260 270 280 290 300
VSYGLMCPAD ETRTIISLDT SQMNRILWVD ENNLTAHVEA GITGQELERQ LKESGYCTGH
310 320 330 340 350 360
EPDSLEFSTV GGWISTRASG MKKNIYGNIE DLVVHMKVVT PRGVIEKSCQ GPRMSTGPDI
370 380 390 400 410 420
HHFIMGSEGT LGVITEATIK IRPTPEYQKY GSVAFPNFEQ GVACLREIAK QRCAPASIRL
430 440 450 460 470 480
MDNQQFQFGH ALKPQVSSIF TSFLDGLKKF YITKFKGFDP NQLSVATLLF EGDREKVLQH
490 500 510 520 530 540
EKQVYDIAAK FGGLAAGEDN GQRGYLLTYV IAYMRDLGLE YYIIGESFET SAPWDRVVDL
550 560 570 580 590 600
CRNVKERIRR ECKEKGVQFP PLSTCRVTQT YDAGACIYFY FAFNYRGISD PLAVFEQTEA
610 620 630 640 650
AAREEILANG GSLSHHHGVG KLRKQWLKES ISDVGFGMLK SVKDYVDPTN IFGNRNLL