Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

4 structures for P96589

Entry ID Method Resolution Chain Position Source
6S3K EM 370 A A/B 1-607 PDB
8B70 EM 330 A A/B 1-607 PDB
8B71 EM 380 A A/B 1-607 PDB
AF-P96589-F1 Predicted AlphaFoldDB

No variants for P96589

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P96589

No associated diseases with P96589

11 regional properties for P96589

Type Name Position InterPro Accession
domain PAS domain 76 - 198 IPR000014
domain PAS-associated, C-terminal 148 - 200 IPR000700
repeat PAC motif 149 - 191 IPR001610
domain Histidine kinase/HSP90-like ATPase 320 - 426 IPR003594
domain Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 214 - 277 IPR003661
domain Signal transduction histidine kinase-related protein, C-terminal 357 - 371 IPR004358-1
domain Signal transduction histidine kinase-related protein, C-terminal 375 - 385 IPR004358-2
domain Signal transduction histidine kinase-related protein, C-terminal 386 - 404 IPR004358-3
domain Signal transduction histidine kinase-related protein, C-terminal 410 - 423 IPR004358-4
domain Histidine kinase domain 221 - 426 IPR005467
domain PAS fold 79 - 188 IPR013767

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
potassium ion transport The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MYHSIKRFLI GKPLKSQAAG EQKLTKLKAL AMLSSDALSS VAYGTEQILI ILATISAAAF
70 80 90 100 110 120
WYSIPIAVGV LILLLALILS YRQIIYAYPQ GGGAYIVSKE NLGEKPGLIA GGSLLVDYIL
130 140 150 160 170 180
TVAVSISAGT DAITSAFPAL HDYHVPIAIF LVLVIMILNL RGLSESASIL AYPVYLFVVA
190 200 210 220 230 240
LLVLIAVGLF KLMTGQIDQP AHHTSLGTPV AGITLFLLLK AFSSGCSALT GVEAISNAIP
250 260 270 280 290 300
AFKNPPARNA ARTLAMMGIL LAILFSGITV LAYGYGTAPK PDETVVSQIA SETFGRNVFY
310 320 330 340 350 360
YVIQGVTSLI LVLAANTGFS AFPQLAFNLA RDQYMPRMFT VRGDRLGFSN GIIFLGFASI
370 380 390 400 410 420
VLIILFGGQT EHLIPLYAVG VFIPFTLSQT GMCMKWIKQK PKGWIGKMLI NSCGALISFM
430 440 450 460 470 480
VLSILFVTKF NVVWPVLIFM PIVVLLFFAI KNHYTAVGEQ LRIVDKEPEE IKGTVVIVPV
490 500 510 520 530 540
AGVTTVVQKS IHYAKSLSDQ VIAVHVSFDR EQEKKFEKRW EELNNGVRLV TLHSSYRSLV
550 560 570 580 590 600
HPFDKFLETV EAKAKKEQFS VMVLFPQFIT KKRWHTILHN QSAFLLRVRL FWKKDIMVAT
LPYHFKK