P95607

PR
Gene name
catA
Protein name
Catechol 1,2-dioxygenase
Names
1,2-CTD
Species
Rhodococcus opacus (Nocardia opaca)
KEGG Pathway
EC number
1.13.11.1: With incorporation of two atoms of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-47 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

11 structures for P95607

Entry ID Method Resolution Chain Position Source
3HGI X-ray 194 A A 1-270 PDB
3HHX X-ray 200 A A 1-270 PDB
3HHY X-ray 155 A A 1-270 PDB
3HJ8 X-ray 240 A A 1-270 PDB
3HJQ X-ray 200 A A 1-270 PDB
3HJS X-ray 180 A A 1-270 PDB
3HKP X-ray 185 A A 1-270 PDB
3I4V X-ray 200 A A 1-270 PDB
3I4Y X-ray 185 A A 1-270 PDB
3I51 X-ray 180 A A 1-270 PDB
AF-P95607-F1 Predicted AlphaFoldDB

No variants for P95607

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P95607

No associated diseases with P95607

2 regional properties for P95607

Type Name Position InterPro Accession
domain Intradiol ring-cleavage dioxygenase, C-terminal 92 - 268 IPR000627
domain Catechol dioxygenase, N-terminal 22 - 87 IPR007535

Functions

Description
EC Number 1.13.11.1 With incorporation of two atoms of oxygen
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
catechol 1,2-dioxygenase activity Catalysis of the reaction: catechol + O2 = cis,cis-muconate.
chlorocatechol 1,2-dioxygenase activity Catalysis of the reaction: 3,6-dichlorocatechol + O2 = 2 H+ + 2,5-dichloro-cis,cis-muconate.
ferric iron binding Binding to a ferric iron ion, Fe(III).

2 GO annotations of biological process

Name Definition
aromatic compound catabolic process The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.
catechol-containing compound metabolic process The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
GSGSAATDKF KAERATADTS PERLAAIAKD ALGALNDVIL KHGVTYPEYR VFKQWLIDVG
70 80 90 100 110 120
EGGEWPLFLD VFIEHSVEEV LARSRKGTMG SIEGPYYIEN SPELPSKCTL PMREEDEKIT
130 140 150 160 170 180
PLVFSGQVTD LDGNGLAGAK VELWHADNDG YYSQFAPHLP EWNLRGTIIA DEEGRYEITT
190 200 210 220 230 240
IQPAPYQIPT DGPTGQFIEA QNGHPWRPAH LHLIVSAPGK ESVTTQLYFK GGEWIDSDVA
250 260
SATKPELILD PKTGDDGKNY VTYNFVLDPA