Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P95539

Entry ID Method Resolution Chain Position Source
AF-P95539-F1 Predicted AlphaFoldDB

No variants for P95539

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P95539

No associated diseases with P95539

5 regional properties for P95539

Type Name Position InterPro Accession
binding_site Catalase haem-binding site 375 - 383 IPR002226
domain Catalase immune-responsive domain 462 - 527 IPR010582
domain Catalase core domain 45 - 433 IPR011614
active_site Catalase active site 81 - 97 IPR024708
domain Large catalase, C-terminal domain 562 - 703 IPR041399

Functions

Description
EC Number 1.11.1.6 Peroxidases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPSKKTDAPK QSEAAGTQTP DRANTNAKLQ SLETFRSDAT GQALRTNQGV KIADNQNSLK
70 80 90 100 110 120
AGARGPSLLE DFIMREKITH FDHERIPERI VHARGTGAHG YFQSYGNHAD LTKAGFLQDP
130 140 150 160 170 180
DKITPVFVRF STVQGPRGSG DTVRDVRGFA VKFYTDEGNF DLVGNNMPVF FIQDAIKFPD
190 200 210 220 230 240
FVHAVKPEPH NEIPTGGSAH DTFWDFVSLV PESAHMVMWA MSDRAIPRSL RMMEGFGVHT
250 260 270 280 290 300
FRLINAEGVA SFVKFHWKPR QGVHSLLWDE AQKLAGKDTD FQRRDLWEAI ENGDYPEWEL
310 320 330 340 350 360
GVQIVPEADE HKFDFDLLDP TKIIPEELVP VTPLGKMVLN RNPDNFFAEV EQVAFCPGHI
370 380 390 400 410 420
VPGIDFTNDP LLQGRLFSYT DTQISRLGGP NFHQIPINRP VAPNHNNQRD ALHQHVVHKG
430 440 450 460 470 480
RASYEPNSID GGWPKETPAA AQDGGFESYQ ERIDAHKIRQ RSESFGDHFS QARLFFQSMS
490 500 510 520 530 540
PTEQQHIIKA YSFELGKVER EHIRAREVNE ILANIDLKLA AAVAANLGLP APKAGTVQVK
550 560 570 580 590 600
GSQLAQSPAL SQMNHPGSVG IKGRKIAVLV ANGVDAASVD KLIKALEAHS ARPMLLGPTS
610 620 630 640 650 660
APVKATDGKQ LPVEASMEGM PSIMFDGIVV PSGKASTDAL AASGLAKHFL LEGYKHLKAM
670 680 690 700 710
VLTKELATGL GLKEDKGLLL ADDQKAVDAF VKAVEGHRVW EREAAAEAVP A