P94507

PR
Gene name
uppP
Protein name
Undecaprenyl-diphosphatase
Names
Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase
Species
Bacillus subtilis (strain 168)
KEGG Pathway
bsu:BSU31150
EC number
3.6.1.27: In phosphorus-containing anhydrides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

53-123 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P94507

Entry ID Method Resolution Chain Position Source
AF-P94507-F1 Predicted AlphaFoldDB

No variants for P94507

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P94507

No associated diseases with P94507

2 regional properties for P94507

Type Name Position InterPro Accession
conserved_site Isocitrate lyase/phosphorylmutase, conserved site 211 - 216 IPR018523
domain ICL/PEPM domain 75 - 489 IPR039556

Functions

Description
EC Number 3.6.1.27 In phosphorus-containing anhydrides
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
undecaprenyl-diphosphatase activity Catalysis of the reaction: di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H+ + phosphate.

5 GO annotations of biological process

Name Definition
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
dephosphorylation The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
peptidoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
regulation of cell shape Any process that modulates the surface configuration of a cell.
response to antibiotic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTLWELFVAA ILGIVEGLTE YAPVSSTGHM IIVDDIWLKS SNLMSEEAAN SFKVVIQLGS
70 80 90 100 110 120
ILAVAIVFKD RILNLLGLKK NITSDQEQGH KLSIAQIAVG LVPAAVLGFL FEDYIDEYLF
130 140 150 160 170 180
SVKTVAIGLI AGAILMLFAD WVNKRKTATD TLDRISYKQA IAVGLFQCLS LWPGFSRSGS
190 200 210 220 230 240
TISGGVILGL NHRAAADFTF IMAMPIMMGA SFLSLVKHWD SLSSDLMPFF IVGFICAFVV
250 260 270
ALFVVRFFLR LINKIKLVPF AIYRIILGVI LLLIMM