Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

12 structures for P93343

Entry ID Method Resolution Chain Position Source
1O9C X-ray 260 A A 1-260 PDB
1O9D X-ray 230 A A 1-260 PDB
1O9E X-ray 260 A A 1-260 PDB
1O9F X-ray 270 A A 1-260 PDB
2O98 X-ray 270 A A/B 1-242 PDB
3E6Y X-ray 250 A A/B 1-260 PDB
3M50 X-ray 260 A A 1-240 PDB
3M51 X-ray 325 A A 1-240 PDB
5NWI X-ray 235 A A 1-260 PDB
5NWJ X-ray 207 A A 1-260 PDB
5NWK X-ray 330 A A/B/C/D/E/F/G/H 1-260 PDB
AF-P93343-F1 Predicted AlphaFoldDB

No variants for P93343

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P93343

No associated diseases with P93343

3 regional properties for P93343

Type Name Position InterPro Accession
conserved_site 14-3-3 protein, conserved site 48 - 58 IPR023409-1
conserved_site 14-3-3 protein, conserved site 220 - 239 IPR023409-2
domain 14-3-3 domain 8 - 251 IPR023410

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
protein localization Any process in which a protein is transported to, or maintained in, a specific location.
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAVAPTAREE NVYMAKLAEQ AERYEEMVEF MEKVSNSLGS EELTVEERNL LSVAYKNVIG
70 80 90 100 110 120
ARRASWRIIS SIEQKEESRG NEEHVNSIRE YRSKIENELS KICDGILKLL DAKLIPSAAS
130 140 150 160 170 180
GDSKVFYLKM KGDYHRYLAE FKTGAERKEA AESTLTAYKA AQDIATTELA PTHPIRLGLA
190 200 210 220 230 240
LNFSVFYYEI LNSPDRACNL AKQAFDEAIA ELDTLGEESY KDSTLIMQLL RDNLTLWTSD
250
MQDDGADEIK EDPKPDEAKN