P93147
Gene name |
CYP81E1 (CYP91A4) |
Protein name |
Isoflavone 2'-hydroxylase |
Names |
CYP GE-3, Cytochrome P450 81E1, Cytochrome P450 91A4 |
Species |
Glycyrrhiza echinata (Licorice) |
KEGG Pathway |
ag:BAA22422 |
EC number |
1.14.14.90: With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P93147
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P93147-F1 | Predicted | AlphaFoldDB |
No variants for P93147
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P93147 | |||||
No associated diseases with P93147
1 regional properties for P93147
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Cytochrome P450, conserved site | 429 - 438 | IPR017972 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.14.90 | With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| iron ion binding | Binding to an iron (Fe) ion. |
| isoflavone 2'-hydroxylase activity | Catalysis of the reaction: an isoflavone + O2 + reduced |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEILSLLSYS | VFYLALFFIF | NIVIRARKFK | NLPPGPPSLP | IIGNLHHLKR | PLHRTFKGLS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EKYGHVFSLW | FGSRLVVVVS | SASEFQQCFT | KNDVVLANRP | RFLSGKYIFY | NYTTLGSTSY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GEHWRNLRRI | TALDVLSNHR | INSFSGIRRD | ETQRLITRLA | DDSSTNFAEM | ELSSRLYDMT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FNNIMRMISG | KRYYGEDCDT | SDLQEASQFR | DMVSELLQLS | GANNKTDFMP | LLRFLDFENL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EKRLKDISGK | TDAFLRGLIE | EHRTKKERAN | TMIDHLLNLQ | DSQPEYYTDQ | IIKGLALAML |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LAGTDSSAVT | LEWSMSNLLN | HPEVLKKVKD | ELDTHVGQDR | LVDESDLPKL | TYLKNVINET |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LRLYTPAPLL | LPHSTSDECN | IGGYKVPQDT | IVLINAWAIH | RDPELWTEAT | TFKPERFEKK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GELEKLIAFG | MGRRACPGEG | LAIRAISMTL | ALLIQCFDWK | LINGDKIDLA | ERDGFTLTKL |
| 490 | |||||
| VPLKAMCKSR | PVINKVFKQ |