P92188

PR
Gene name
Protein name
Proteasome subunit alpha type-1
Names
Proteasome 29 kDa subunit, TCPR29
Species
Trypanosoma cruzi
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

213-265 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P92188

Entry ID Method Resolution Chain Position Source
AF-P92188-F1 Predicted AlphaFoldDB

No variants for P92188

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P92188

No associated diseases with P92188

3 regional properties for P92188

Type Name Position InterPro Accession
domain Neurotransmitter-gated ion-channel transmembrane domain 243 - 456 IPR006029
domain Neurotransmitter-gated ion-channel ligand-binding domain 33 - 235 IPR006202
conserved_site Neurotransmitter-gated ion-channel, conserved site 156 - 170 IPR018000

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
proteasome core complex, alpha-subunit complex The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFKNQYDTNT TTWSPTGRLF QVEYANEAVN NGSAAVGAKN KDFVVLTALK RSPVAQFSSY
70 80 90 100 110 120
QEKVFKLDDH VGMAIAGLVA DGRMLARFVR TECMNYRYMH DSDNPLPLIA EIVGEKYQRH
130 140 150 160 170 180
IQFAGKRPFG VGLLIAGYDS TGPHLYHTVP SGDVFDFKAT AMGLRSQAAR TYLEKHFESF
190 200 210 220 230 240
PDCGLDELIM HALKALAAAT SGGAELNIKN TTIAIVGKGT PFMVLTEEAA RKYLDGFKMR
250 260
PEDIPPAPEA EEEETLQERS LDVEE