P92029
Gene name |
srd-26 (T02B5.4) |
Protein name |
DnaJ-like protein 60 |
Names |
|
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG42567 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P92029
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P92029-F1 | Predicted | AlphaFoldDB |
No variants for P92029
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P92029 | |||||
No associated diseases with P92029
1 regional properties for P92029
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | DnaJ domain | 25 - 93 | IPR001623 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| unfolded protein binding | Binding to an unfolded protein. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| protein refolding | The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. |
| response to heat | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. |
| spermatogenesis | The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9D844 | Dnajc4 | DnaJ homolog subfamily C member 4 | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLRLCLPTRA | GYVRNFSNDK | PRKPETHYEV | LNIRNDCSTR | EVRNAFVQLS | KLYHPDVKSN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AACPERTARF | VQISEAYKTL | IKPERRRDYD | DSLLWQPSRS | DRSPVGETVN | PGQAWDVRPN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YDPNPGPYYG | IRGLKRVSNW | QVAVVLMALG | FVGALFGFTS | VRSSFKLSRQ | IQDEISAEAN |
| 190 | 200 | 210 | |||
| SHHAAVVADA | QKYGNEEQVR | RMVDRMSRSP | FNQSSAK |